Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice. [PDF]
, 2010 An ongoing controversy exists on beneficial versus harmful effects of high beta-carotene (BC) intake, especially for the lung. To elucidate potential mechanisms, we studied effects of BC on lung gene expression.
Amengual, J. +9 more
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The molecular aspects of absorption and metabolism of carotenoids and retinoids in vertebrates.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2019 Vitamin A is an essential nutrient necessary for numerous basic physiological functions, including reproduction and development, immune cell differentiation and communication, as well as the perception of light.
M. A. Widjaja-Adhi, M. Golczak
semanticscholar +1 more source
Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra. [PDF]
, 2017 Acne fulminans (AF) is a severe form of inflammatory and ulcerated acne associated with fever, malaise, joint swellings and polyarthralgia.1 Osteoarticular lesions are often described and can be radiologically indistinguishable from those observed in
Barbareschi +9 more
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Why Topical Retinoids Are Mainstay of Therapy for Acne
Dermatologic Therapy, 2017 Acne-focused dermatology expert groups have consistently recommended that most patients with acne be treated with a combination of topical retinoid and antimicrobial therapy. This is based on clinical data as well as evidence that these drug classes have
J. Leyden +2 more
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The role of the retinoids in schizophrenia: genomic and clinical perspectives
Molecular Psychiatry, 2019 Signalling by retinoid compounds is vital for embryonic development, with particular importance for neurogenesis in the human brain. Retinoids, metabolites of vitamin A, exert influence over the expression of thousands of transcripts genome wide, and ...
W. Reay, M. Cairns
semanticscholar +1 more source
Role of vitamin A/retinoic acid in regulation of embryonic and adult hematopoiesis [PDF]
, 2017 Vitamin A is an essential micronutrient throughout life. Its physiologically active metabolite retinoic acid (RA), acting through nuclear retinoic acid receptors (RARs), is a potent regulator of patterning during embryonic development, as well as being ...
Adamo +23 more
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Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids
International Journal of Molecular Sciences, 2018 Retinoids represent a popular group of differentiation inducers that are successfully used in oncology for treatment of acute promyelocytic leukemia in adults and of neuroblastoma in children.
P. Chlapek +4 more
semanticscholar +1 more source
BMC Cancer, 2018 For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies have reported the promising role of retinoids
Viera Dobrotkova +4 more
semanticscholar +1 more source
Revival of the Russian chemical industry during the Soviet period (1917–1927). Part 4
Разработка и регистрация лекарственных средств, 2023 This section contains appendices to the previous 4 parts of the article. These applications are important because they document every step taken by the leadership of the young Soviet Republic, and then the USSR, to restore the domestic chemical industry ...
K. S. Guzev
doaj
Erythema nodosum induced by oral isotretinoin in a patient with condylomata acuminata [PDF]
, 2020 Erythema nodosum (EN) is a form of septal panniculitis, which is believed to represent a delayed hypersensitivity reaction activated by infectious agents, drugs, granulomatous and autoimmune diseases, pregnancy, and malignancies.
Badavanis, George +4 more
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