Results 31 to 40 of about 77,321 (327)
YAKUGAKU ZASSHI, 1996 Retinoids, retinoic acid and its bioisosters, regulate many biological functions such as cell differentiation, proliferation and embryonic development in vertebrates, through binding to and activating their specific nuclear receptors. There are two classes of nuclear receptors for retinoids, retinoic acid receptors (RAR alpha, beta, gamma) and retinoid
H, Umemiya +4 more
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Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]
, 2014 Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
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Retinoids in cancer chemoprevention and therapy: Meta-analysis of randomized controlled trials
Frontiers in Genetics, 2022 Retinoids, natural and synthetic derivatives of vitamin A, have many regulatory functions in human body, including regulating cellular proliferation, differentiation, apoptosis. Moreover, retinoids have been used successfully for the treatment of certain
Shuting Chen +20 more
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Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]
, 2020 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
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Retinoid-binding proteins: mediators of retinoid action [PDF]
Biochemical Journal, 2000 Active vitamin A metabolites, known as retinoids, are essential for multiple physiological processes, ranging from vision to embryonic development. These small hydrophobic compounds associate in vivo with soluble proteins that are present in a variety of cells and in particular extracellular compartments, and which bind different types of retinoids ...
openaire +2 more sources
Revival of the Russian chemical industry during the Soviet period (1917–1927). Part 4
Разработка и регистрация лекарственных средств, 2022 The fourth chapter presents V. N. Ipatiev's memoirs about the preparation and celebration of the 200th anniversary of the Russian Academy of Sciences and the next Mendeleev Congress.
K. S. Guzev
doaj
Pharmaceutics, 2022 Retinoids, one of the most robust bioactive materials, have been widely used to improve various dermatological and pathological conditions. The body has an endogenous mechanism that modulates the exogenous retinoid above physiological concentrations ...
Seongsu Kang +4 more
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RPB4 and pathogenesis of diabetes [PDF]
, 2007 Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh +1 more
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Singlet Oxygen and Free Radical Reactions of Retinoids and Carotenoids—A Review
Antioxidants, 2018 We report on studies of reactions of singlet oxygen with carotenoids and retinoids and a range of free radical studies on carotenoids and retinoids with emphasis on recent work, dietary carotenoids and the role of oxygen in biological processes.
R. Edge, T. Truscott
semanticscholar +1 more source
Разработка и регистрация лекарственных средств, 2023 The second part of the article presents the next steps of Peter the Great to improve the functioning of the pharmacy service in Russia. To improve the management of the nascent pharmacy service, the Emperor established the Main Pharmacy in the ...
K. S. Guzev
doaj