Results 11 to 20 of about 30,549 (287)
Retinoids – A Perspective To Teratogenic Effects
Journal of Dentistry Indonesia, 2015 Since the role of retinoids in normal growth, reproduction, maintenance and differentiantion of epithelial tissue has been known, the therapeutic value of retinoids has been utilised in disorders resembling vitamin A (retinol) deficiency. Much effort has
Elza Ibrahim Auerkari
doaj +2 more sources
The Origin of Teratogenic Retinoids in Cyanobacteria
Toxins, 2022 Although information about the occurrence and distribution of retinoids in the environment is scarce, cyanobacterial water blooms have been identified as a significant source of these small molecules.
Luděk Sehnal +5 more
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Annual Review of Pharmacology and Toxicology, 1999 Either an excess or a deficiency of vitamin A and related compounds (retinoids) causes abnormal morphological development (teratogenesis). Potential retinoid sources come from dietary intake, nutritional supplements, and some therapeutic drugs. Therefore, understanding the mechanisms of retinoid teratogenesis is important.
M D, Collins, G E, Mao
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Retinoids, Apoptosis and Cancer
Current Pharmaceutical Design, 2001 Retinoids are a class of natural and synthetic vitamin A analogs structurally related to all-trans-retinoic acid (ATRA). Natural retinoids are involved in the physiology of vision and as morphogenic agents during embryonic development; they are also known to play a major role in regulating growth and differentiation of a wide variety of normal and ...
SIMONI, Daniele, TOLOMEO M.
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Retinoids are analogs of vitamin A that exert multiple effects on cellular differentiation and proliferation, the immune system, and embryonic development.
Sorg, Olivier, Saurat, Jean-Hilaire
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, 2010 Chapter one is split into three sections, providing general overviews of synthetic retinoids and their biology, Pd-catalysed C-C bond forming reactions and transition metal-catalysed borylation of aromatic and vinylic C-H bonds, respectively. Chapter two
Barnard, Jonathan Harold
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Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
, 2023 Vitamin A is present in the skin where it plays a crucial role in epidermal turnover. Nutritional vitamin A deficiency, exposure to sunlight or any ultraviolet (UV) source, oxidative stress, and chronological aging may lead to epidermal vitamin A ...
Sorg, Olivier, Saurat, Jean-Hilaire
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Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Retinoids and Retinoid Receptors in Teratogenesis* [PDF]
Congenital Anomalies, 1995 AbstractThere is overwhelming evidence that vitamin A (retinol), presumably through its metabolite retinoic acid, participates in organogenesis at several stages and sites during normal development. Besides the important role of retinol and retinoic acid (RA) as micronutrients in growth and development, these retinoids and their synthetic analogs are ...
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