Results 51 to 60 of about 27,382 (293)
Therapeutic insights elaborating the potential of retinoids in Alzheimer’s disease
Alzheimer’s disease (AD) is perceived with various pathophysiological characteristics such oxidative stress, senile plaques, neuroinflammation, altered neurotransmission immunological changes, neurodegenerative pathways, and age-linked alterations.
Tapan Behl +11 more
doaj +1 more source
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu +12 more
wiley +1 more source
Sythesis of retinoic acid analogues & investigations into their ability to induce stem cell differentation [PDF]
Human embryogenesis and ensuing adult homeostasis are directed by the complex interplay of a wide range of exquisitely controlled signalling molecules and pathways. All-trans-retinoic acid (ATRA) is one such important hormone-like compound that regulates
Bridgens, Caroline Emma
core
RETINOIDS IN DERMATOLOGY:FUNCTIONAL ACTIVITY AND PROSPECTS OF SYNTHETIC ANALOGUES
The aim of the work was to analyze and summarize information on the functional activity of known retinoids, as well as to determine the directions of their modification and prospects for the use of their synthetic analogues in dermatology.
V. B. KOVTUN
doaj +1 more source
Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana +5 more
wiley +1 more source
Retinoids are structural and functional analogues of vitamin A that exert multiple effects on cellular differentiation and proliferation, the immune system, and embryonic development Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are ...
Sorg, Olivier, Saurat, Jean-Hilaire
core
Modulation of Differentiation by Retinoids [PDF]
At high levels of vitamin A and other retinoids (3 × 10-6 M) attachment of human keratinocytes to 3T3-coated plastic dishes is mildly inhibited, Retinoids at this concentration in culture media seem to have an antikeratinizing effect in that cells appear
Kubilus, Joseph
core +1 more source
Retinoids in Fungal Infections: From Bench to Bedside
Retinoids—a class of chemical compounds derived from vitamin A or chemically related to it—are used especially in dermatology, oncohematology and infectious diseases.
Terenzio Cosio +7 more
doaj +1 more source
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang +10 more
wiley +1 more source
Binding of retinoids to uteroglobin [PDF]
Uteroglobin, a progesterone-binding secretory protein, was shown to bind retinoic acid and retinol in a non-saturable manner, at least up to concentrations of retinoids of 20 μM.
Martinez, M.Pérez +7 more
core +1 more source

