Results 171 to 180 of about 77,321 (327)

Divergent System Organ Class Safety Profiles of Isotretinoin Versus Topical Retinoids: An EudraVigilance Disproportionality Analysis. [PDF]

Pharmaceuticals (Basel)
Szilagyi DV, Tit DM, Marin RC, Bungau GS, Toma MM, Pasca MB, Gitea D, Endres LM.   +7 more
europepmc   +1 more source

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.

Cancer Cell, 2015
M. Churchman, J. Low, Chunxu Qu, E. Paietta, L. Kasper, Yunchao Chang, D. Payne-Turner, M. Althoff, Guangchun Song, Shann-Ching Chen, Jing Ma, M. Rusch, D. McGoldrick, Michael N. Edmonson, P. Gupta, Y. D. Wang, W. Caufield, B. Freeman, Lie Li, J. Panetta, S. Baker, Yung‐Li Yang, K. Roberts, K. McCastlain, I. Iacobucci, Jennifer L. Peters, V. Centonze, F. Notta, F. Notta, Stephanie M. Dobson, Stephanie M. Dobson, Sasan Zandi, Sasan Zandi, J. Dick, J. Dick, L. Janke, Junmin Peng, K. Kodali, V. Pagala, Jaeki Min, Anand Mayasundari, R. Williams, C. Willman, J. Rowe, S. Luger, R. Dickins, R. Guy, Taosheng Chen, C. Mullighan   +48 more
semanticscholar   +1 more source

Functionally related internal fluctuations in human ileal bile acid‐binding protein by high pressure nuclear magnetic resonance

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Hidden protein states with partially unfolded regions can have a functional relevance and may also contribute to an uncontrolled self‐association of proteins leading to pathological conditions. Human ileal bile acid‐binding protein (hI‐BABP), a member of the family of intracellular lipid‐binding proteins (iLBPs), plays a key role in the ...
Tamara Teski, Bence Balterer, Gergő Horváth, Gábor Turczel, Orsolya Toke   +4 more
wiley   +1 more source

Illuminating retinoid flux in the neurosensory retina. [PDF]

J Clin Invest
Moshiri A, Sodhi A.
europepmc   +1 more source

Bioconversion of carotenoids into high‐value crocins using a marine sponge carotenoid cleavage dioxygenase

New Phytologist, Volume 250, Issue 5, Page 3230-3246, June 2026.
Summary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Elena Moreno‐Giménez, Lucía Morote, Alberto José López Jiménez, Eduardo Parreño, Jian You Wang, Matteo Nava, Carolina Aguado, Rafael Luján, Salim Al‐Babili, Gianfranco Diretto, Oussama Ahrazem, Lourdes Gómez‐Gómez   +11 more
wiley   +1 more source

Association of retinoids, retinoic acid receptors and epigenetics in breast cancer. [PDF]

Oncogene
Szymański Ł, Schenk T, Ławiński M, Brioli A, Zelent A.   +4 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

New Mechanistic Evidence for Perfluorodecanoic Acid (PFDA) Teratogenicity via CYP26A1-Mediated Retinoic Acid Metabolism and Signaling. [PDF]

Chem Res Toxicol
Hvizdak M, Kandel SE, Lampe JN.
europepmc   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Bridging Gaps in Malaysian Acne Vulgaris Guidelines: Advisory Statements on Trifarotene for Facial and Truncal Acne. [PDF]

J Cosmet Dermatol
Mohd Affandi A, Ch'ng PWB, Teoh BTY, Yap EWY, Ch'ng CC, Foo SH, How KN, Kwan Z, Tang JJ, Tan WC, Kon K, Poh WT.   +11 more
europepmc   +1 more source