Adipokine Retinol Binding Protein 4 and Cardiovascular Diseases [PDF]
Frontiers in Physiology, 2022 The morbidity and mortality of cardiovascular diseases (CVDs) have been increasing year by year all over the world and expanding greatly to the younger population, which becomes the leading causes of death globally that threatens human life safety ...
Yanjing Ji +3 more
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Retinol-binding protein-4 and nonalcoholic fatty liver disease [PDF]
Chinese Medical Journal, 2022 . Nonalcoholic fatty liver disease (NAFLD) is becoming increasingly common as the global economy grows and living standards improve. Timely and effective preventions and treatments for NAFLD are urgently needed.
Hangkai Huang, Chengfu Xu, Yuanyuan Ji
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Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study [PDF]
BMC Pulmonary MedicineBackground The Corona Virus Disease 2019 (COVID-19) pandemic has struck globally. Whether the related proteins of retinoic acid (RA) signaling pathway are causally associated with the risk of COVID-19 remains unestablished.
Haixia Wang +5 more
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Retinol-binding protein 4 in cardiovascular diseases: mechanisms and therapeutic perspectives [PDF]
Frontiers in Cardiovascular MedicineCardiovascular diseases (CVDs) continue to be the leading cause of mortality worldwide, highlighting the need for enhanced diagnostic tools to enable early intervention.
Jiefang Chen +4 more
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Electrochemical Aptasensing Platform for the Detection of Retinol Binding Protein-4 [PDF]
BiosensorsHere, we present the results of our the electrochemical aptasensing strategy for retinol binding protein-4 (RBP-4) detection based on a thiolated aptamer against RBP-4 and 6-mercaptohexanol (MCH) directly immobilized on a gold electrode surface. The most
Kamila Malecka-Baturo +4 more
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Retinol binding protein 4 enhances cellular cholesterol uptake to facilitate influenza A virus infection [PDF]
PLoS PathogensViruses hijack host cell machinery to facilitate their own replication. Therefore, identifying key cellular factors and processes involved in viral infection is crucial for developing host-directed therapies.
Hejiao Zhao +6 more
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Retinol binding protein 4 restricts PCV2 replication via selective autophagy degradation of viral ORF1 protein [PDF]
Communications BiologyAutophagy is a highly conserved degradative process that has been linked to various functions, including defending host cells against pathogens. Although the involvement of autophagy in porcine circovirus 2 (PCV2) infection has become apparent, it ...
Qingbing Han +6 more
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A Label-Free Gold Nanoparticles-Based Optical Aptasensor for the Detection of Retinol Binding Protein 4 [PDF]
Biosensors, 2022 Retinol-binding protein 4 (RBP4) has been implicated in insulin resistance in rodents and humans with obesity and T2DM, making it a potential biomarker for the early diagnosis of T2DM.
Koena L. Moabelo +6 more
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Elevated Serum Retinol Binding Protein 4 is Associated with the Risk of Diabetic Cardiomyopathy [PDF]
Reviews in Cardiovascular Medicine, 2022 Background: Retinol binding protein 4 (RBP4), a biomarker for insulin resistance in type 2 diabetes (DM), is increased in heart failure. This case-control study aims to determine the association between serum RBP4 levels and diabetic cardiomyopathy (DCM).
Haihua Shan +8 more
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Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression [PDF]
Journal of Lipid Research, 2022 Hepatocytes secrete retinol-binding protein 4 (RBP4) into circulation, thereby mobilizing vitamin A from the liver to provide retinol for extrahepatic tissues. Obesity and insulin resistance are associated with elevated RBP4 levels in the blood. However,
Julia S. Steinhoff +17 more
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