The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review. [PDF]
Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in which tubular injury is the driving force.
Ratajczyk K +8 more
europepmc +5 more sources
Retinol Binding Protein 4 and Pathogenesis of Diabetes [PDF]
Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Philip G. McTernan, Sudhesh Kumar
openaire +3 more sources
Role of retinol-binding protein 4 in obese Asian Indians with metabolic syndrome [PDF]
Retinol-binding protein 4 is an adipocytokine separately implicated in the development of obesity-related insulin resistance and proatherogenic lipid profile, however, its role in humans is unclear.
Shivakumar Nirupama +8 more
doaj +2 more sources
High resolution crystal structure data of human plasma retinol-binding protein (RBP4) bound to retinol and fatty acids [PDF]
Retinol is transported in vertebrate plasma bound to a protein called retinol-binding protein (RBP4) so far believed to be specific for the vitamin. When the protein is saturated with retinol it binds tightly to another plasma protein, transthyretin ...
Massimiliano Perduca +4 more
doaj +2 more sources
Relationship of Retinol Binding Protein Four Serum Level on Endometrial Hyperplasia and Endometrial Carcinoma [PDF]
Objective : To determine the relationship of elevated serum retinol binding protein 4 with abnormal uterine bleeding Methods : This study was an observational quantitative with cross sectional methods, with all women who had abnormal uterine bleeding ...
Ivan Limy +2 more
doaj +2 more sources
Retinol Binding Protein 4 in Non Obese Psoriatic Cases [PDF]
Ola Ahmed Bakry +3 more
doaj +3 more sources
Retinol-binding protein-4 was associated with sensitization to inhalant allergens in the elderly population [PDF]
Background/Aims Recent evidence suggests an association between allergic sensitization and metabolic markers. However, this association has rarely been examined in the elderly.
Byung-Keun Kim +7 more
doaj +1 more source
Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction [PDF]
Dissociation of transthyretin (TTR) tetramers may lead to misfolding and aggregation of pro-amyloidogenic monomers, which underlies TTR amyloidosis (ATTR) pathophysiology.
Arun, Raja +7 more
core +1 more source
Polyclonal aptamer libraries as binding entities on a graphene FET based biosensor for the discrimination of apo- and holo- retinol binding protein 4 [PDF]
Oligonucleotide DNA aptamers represent an emergently important class of binding entities towards as different analytes as small molecules or even whole cells.
Ann-Kathrin , Kissmann +9 more
core +2 more sources
SERUM LEVEL OF RETINOL BINDING PROTEIN 4 IN RELATION TO AMYOTROPHIC LATERAL SCLEROSIS AMONG EGYPTIAN PATIENTS [PDF]
Background: Amyotrophic lateral sclerosis is a progressive devastating neurodegenerative disorder. It is characterized by both upper and lower motor neuron degeneration, leading to progressive skeletal muscle atrophy, paralysis, and consequent death. The
Rasha Mohamed Mamdouh +4 more
doaj +1 more source

