Results 91 to 100 of about 2,216,238 (221)

Alterations to oxidative stress markers in dogs after a short-term stress during transport*

open access: yesJournal of Nutritional Science, 2014
While methods to evaluate antioxidant capacity in animals exist, one problem with the models is induction of oxidative stress. It is necessary to promote a great enough challenge to induce measurable alterations to oxidative parameters while ensuring the
Chayanne S. Ferreira   +8 more
doaj   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

open access: yesBrain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu   +11 more
wiley   +1 more source

Retinol binding protein 4 and retinol in steatotic and nonsteatotic rat livers in the setting of partial hepatectomy under ischemia/reperfusion

open access: yes, 2012
Steatotic livers show increased hepatic damage and impaired regeneration after partial hepatectomy (PH) under ischemia/reperfusion (I/R), which is commonly applied in clinical practice to reduce bleeding.
Mendes-Braz, Mariana   +13 more
core   +1 more source

Kinetic studies of retinol addition radicals

open access: yes, 2021
Retinol neutral radicals (RS-retinol), generated from the reaction of retinol with 4-pyridylthiyl and 2-pyridylthiyl radicals in argon-saturated methanol, undergo β-elimination, which can be monitored via the slow secondary absorption rise at 380 nm ...
Shunichi Fukuzumi
core   +1 more source

Structural and biochemical basis for retinol‐binding protein 4 antagonism by tinlarebant

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Retinol‐binding protein 4 (RBP4) is a member of the lipocalin superfamily that is connected to disease states such as insulin resistance, fatty liver disease and ocular disorders including Stargardt disease. Several retinoid and non‐retinoid antagonists of this protein have been developed for potential clinical use, but none have
Marco Bassetto, Philip D. Kiser
wiley   +1 more source

Cardiometabolic Protein Profile Changes During Gender‐Affirming Hormone Therapy: A Prospective Clinical Study

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Cardiovascular disease (CVD) risk is elevated in transgender individuals during gender‐affirming hormone therapy (GAHT) with expected different mechanisms between T‐ and E2‐based GAHT. We investigated prospective changes in cardiometabolic proteins relating to complement, inflammation, and transport during GAHT.
Emilie Bukh Madsen   +12 more
wiley   +1 more source

Structural and binding properties of two paralogous fatty acid binding proteins of Taenia solium metacestode.

open access: yesPLoS Neglected Tropical Diseases, 2012
BackgroundFatty acid (FA) binding proteins (FABPs) of helminths are implicated in acquisition and utilization of host-derived hydrophobic substances, as well as in signaling and cellular interactions. We previously demonstrated that secretory hydrophobic
Seon-Hee Kim   +7 more
doaj   +1 more source

Histological manifestations of vitamin A toxicity in the liver

open access: yesHistopathology, EarlyView.
Analysing clinicopathological data from 1960 to 2025, this study characterizes the spectrum of liver injury associated with chronic vitamin A toxicity. Hepatic stellate cell hypertrophy/hyperplasia and sinusoidal fibrosis emerge as the predominant features, providing a morphological basis for diagnosing vitamin A hepatotoxicity.
Giorgio Cazzaniga   +2 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Retinol Uptake by Isolated Retinol Pigment Epithelium Plasma Membranes

open access: yes, 1981
The uptake of retinol has been investigated by incubating suspensions of isolated bovine retinal pigment epithelium plasma membranes in the presence of [3H]retinol-retinol-binding protein complex. After SDS gel electrophoresis of the labelled membranes, [
OTTONELLO, Simone   +3 more
core   +1 more source

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