Strict retroelement regulation is frequently lost following cancer transformation and generates a promising reservoir of cancer biomarkers [PDF]
Mobile DNABackground Retroelements are repetitive sequences that comprise 42% of the human genome and are strictly regulated through various epigenetic mechanisms.
Eric Russ, Sergey Iordanskiy
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Contrasting distributions and expression characteristics of transcribing repeats in Setaria viridis [PDF]
The Plant GenomeRepetitive DNA contributes significantly to plant genome size, adaptation, and evolution. However, little is understood about the transcription of repeats. This is addressed here in the plant green foxtail millet (Setaria viridis).
Ana Luiza Franco +5 more
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Retroelements versus APOBEC3 family members: No great escape from the magnificent seven [PDF]
Frontiers in Microbiology, 2012 Retroelements comprise a large and successful family of transposable genetic elements that, through intensive infiltration, have shaped the genomes of humans and other mammals over millions of years.
Juan F Arias +3 more
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Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses [PDF]
Retrovirology, 2012 Background The identification of cellular factors that regulate the replication of exogenous viruses and endogenous mobile elements provides fundamental understanding of host-pathogen relationships.
Arjan-Odedra Shetal +4 more
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Expression of the Nicotiana benthamiana Retrozyme 1 (NbRZ1) Genomic Locus [PDF]
PlantsRetrozymes are a class of non-autonomous plant retrotransposons that have long terminal repeats (LTRs) containing hammerhead ribozymes (HHRs) that facilitate the circularization of the retrozyme RNA.
Alexander A. Lezzhov +4 more
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Role of Retroelements in Frontotemporal Dementia Development [PDF]
Frontiers in Bioscience-ScholarFrontotemporal dementia (FTD) develops in proteinopathies involving TDP-43 (transactive response DNA-binding protein 43 kDa), tau, and FUS (fused in sarcoma) proteins, which possess antiviral properties and exert inhibitory effects on human transposable ...
Rustam Nailevich Mustafin
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Diel expression dynamics in filamentous cyanobacteria [PDF]
mBioFilamentous cyanobacteria of the Nostocaceae family can differentiate into multicellular forms to adapt to environmental stresses, and members can establish symbiosis with various embryophytes.
Sarah J. Kennedy +2 more
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The role of retroelements in Parkinson’s disease development [PDF]
Вавиловский журнал генетики и селекцииParkinson’s disease is the second most common neurodegenerative disease characterized by accumulation of alpha-synuclein and Lewy bodies in the brain’s substantia nigra.
R. N. Mustafin
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The evolutionary entanglement of flipons with zinc fingers and retroelements has engendered a large family of Z-DNA and G-quadruplex binding proteins. [PDF]
Open BiolHerbert A.
europepmc +2 more sources
Association between Human Endogenous Retrovirus K gene expression and breast cancer [PDF]
Cellular, Molecular and Biomedical Reports, 2021 Breast cancer is one of the most common cancers known, and it is also a significant cause of death in women. If breast cancer is diagnosed in the early stages of the disease and treated appropriately, we can see an increase in life expectancy for more ...
Masoud Tourang +3 more
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