Results 31 to 40 of about 474 (133)

Retroelement origins of pre‐mRNA splicing [PDF]

WIREs RNA, 2020
AbstractRecent cryo‐EM structures of a group II intron caught in the process of invading DNA have given new insight into the mechanisms of both splicing and retrotransposition. Conformational dynamics involving the branch‐site helix domain VI are responsible for substrate exchange between the two steps of splicing.
Daniel B. Haack, Navtej Toor
openaire   +2 more sources

The Method of Viral Mimicry in Oncology and Prospects for its Improvement

Архивъ внутренней медицины, 2023
Malignant neoplasms cells are characterized by clonal evolution that is resistant to the applied antitumor drug and evasion from the effects of the immune system.
R. N. Mustafin
doaj   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

High‐quality genome of elite peanut cultivar ZH05 reveals subgenome asymmetry, pan‐genome diversity, and breeding insights

Journal of Integrative Plant Biology, EarlyView.
A high‐quality reference genome for the elite peanut cultivar Zhonghua No. 5 revealed differing evolutionary paths between the two peanut subgenomes. SubA has higher overall gene expression and more open chromatin, whereas SubB has stronger structural organization, higher DNA methylation, and greater adaptive diversity associated with peanut evolution ...
Taihua Yang, Nian Liu, Li Huang, Jianbin Guo, Xiaomeng Xue, Mingjun Wang, Xiaohan Zhang, Chengtao Quan, Enyou Feng, Jiazhuang Tan, Zhenzhen Zhang, Yu You, Youlin Xia, Dongxin Huai, Yuning Chen, Liyin Yan, Kede Liu, Huifang Jiang, Yong Lei, Boshou Liao   +19 more
wiley   +1 more source

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

Cells, 2019
Background: Retroelements (REs) are mobile genetic elements comprising ~40% of human DNA. They can reshape expression patterns of nearby genes by providing various regulatory sequences.
Daniil Nikitin, Nikita Kolosov, Anastasiia Murzina, Karina Pats, Anton Zamyatin, Victor Tkachev, Maxim Sorokin, Philippe Kopylov, Anton Buzdin   +8 more
doaj   +1 more source

Whole Genome Assembly and Annotation of Two Invasive Sitona Species

Journal of Applied Entomology, Volume 150, Issue 8, Page 1025-1034, September 2026.
ABSTRACT Weevils are a highly diversified taxon, comprising about 70,000 described species, including many of high economic importance. Here, we present whole genome assemblies and annotations of two Sitona species (Coleoptera: Curculionidae: Entiminae).
Mandira Katuwal, Upendra Raj Bhattarai, Craig B. Phillips, Neil J. Gemmell, Eddy Dowle   +4 more
wiley   +1 more source

Contrasting distributions and expression characteristics of transcribing repeats in Setaria viridis

The Plant Genome
Repetitive DNA contributes significantly to plant genome size, adaptation, and evolution. However, little is understood about the transcription of repeats. This is addressed here in the plant green foxtail millet (Setaria viridis).
Ana Luiza Franco, Wenjia Gu, Petr Novák, Ilia J. Leitch, Lyderson F. Viccini, Andrew R. Leitch   +5 more
doaj   +1 more source

Distribution of a Ty3/gypsy-like retroelement on the A and B-chromosomes of Cestrum strigilatum Ruiz & Pav. and Cestrum intermedium Sendtn. (Solanaceae)

Genetics and Molecular Biology, 2007
Retroelements are a diversified fraction of eukaryotic genomes, with the Ty1/copia and Ty3/gypsy groups being very common in a large number of plant genomes. We isolated an internal segment of the Ty3/gypsy retroelement of Cestrum strigilatum (Solanaceae)
Jéferson Nunes Fregonezi, Laurival A. Vilas-Boas, Maria Helena Pelegrinelli Fungaro, Marcos Letaif Gaeta, André Luís Laforga Vanzela   +4 more
doaj   +1 more source

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

Plant, Cell &Environment, Volume 49, Issue 9, Page 6506-6520, September 2026.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang, Daqi Yan, Jiayi Hou, Dan Yang, Yan Xiong, Mingzhang Wen, Xiaoyue Zhu   +6 more
wiley   +1 more source

HIV/AIDS Pandemia — a Problem Requiring Rethinking On the 30th Anniversary of the Discovery of Human Immunodeficiency Virus

Aktualʹnaâ Infektologiâ, 2014
Hazard of HIV/AIDS pandemia is greatly underestimated due to lack of understanding of its role in the processes that are not related to medicine. The principal difference between HIV/AIDS pandemia and the pandemic processes, against which the advances ...
M.V. Supotnitsky
doaj   +1 more source