Results 21 to 30 of about 14,990 (203)
BMC Genomics, 2007 Background LTR retrotransposons are a class of mobile genetic elements containing two similar long terminal repeats (LTRs). Currently, LTR retrotransposons are annotated in eukaryotic genomes mainly through the conventional homology searching approach ...
Kim Sun +4 more
doaj +4 more sources
Involvement of retroelements in the autoimmune response in humans
Exploration of Medicine, 2022 Retroelements are mobile genomic components requiring an RNA intermediate which is reverse-transcribed into complementary DNA for transposition. Human genome contains a vast amount of retroelements including retrotransposons and endogenous retroviruses ...
Sezer Okay
doaj +1 more source
Prospects for the use of statins in antiviral therapy [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 Inhibitors of hydroxymethylglutaryl-CoA reductase, in addition to suppressing cholesterol synthesis, have an antiviral effect. Clinical studies have shown antiviral efficacy of statins against COVID-19, HCV, HBV, RSV, HIV, influenza viruses.
Mustafin R.N.
doaj +1 more source
Large-scale transcriptome analysis of retroelements in the migratory locust, Locusta migratoria. [PDF]
PLoS ONE, 2012 BackgroundRetroelements can successfully colonize eukaryotic genome through RNA-mediated transposition, and are considered to be some of the major mediators of genome size.
Feng Jiang +4 more
doaj +1 more source
Association between Human Endogenous Retrovirus K gene expression and breast cancer [PDF]
Cellular, Molecular and Biomedical Reports, 2021 Breast cancer is one of the most common cancers known, and it is also a significant cause of death in women. If breast cancer is diagnosed in the early stages of the disease and treated appropriately, we can see an increase in life expectancy for more ...
Masoud Tourang +3 more
doaj +1 more source
The evidence for increased L1 activity in the site of human adult brain neurogenesis. [PDF]
PLoS ONE, 2015 Retroelement activity is a common source of polymorphisms in human genome. The mechanism whereby retroelements contribute to the intraindividual genetic heterogeneity by inserting into the DNA of somatic cells is gaining increasing attention.
Alexey A Kurnosov +9 more
doaj +1 more source
Role Of Retroelements In The Development Of COVID-19 Neurological Consequences [PDF]
, 2022 Retroelements play a key role in brain functioning in humans and other animals, since they represent dynamic regulatory elements controlling the expression of specific neuron types.
Kazantseva, Anastasiya V. +3 more
core +1 more source
Frontiers in Immunology, 2020 More than 200 human disorders include various manifestations of autoimmunity. The molecular events that lead to these diseases are still incompletely understood and their causes remain largely unknown.
Tomas Mustelin, Kennedy C. Ukadike
doaj +1 more source
DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA. [PDF]
, 2017 Diversity-generating retroelements (DGRs) are molecular evolution machines that facilitate microbial adaptation to environmental changes. Hypervariation occurs via a mutagenic retrotransposition process from a template repeat (TR) to a variable repeat ...
Guo, Huatao +6 more
core +3 more sources
Frontiers in Microbiology, 2021 The human genome bears evidence of extensive invasion by retroviruses and other retroelements, as well as by diverse RNA and DNA viruses. High frequency of somatic integration of the RNA virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ...
Anastasiya Kazachenka +2 more
doaj +1 more source