Results 61 to 70 of about 14,990 (203)

Transposable Elements, Inflammation, and Neurological Disease. [PDF]

, 2019
Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela, Muotri, Alysson R, Saleh, Aurian   +2 more
core  

LTR-retrotransposons from Bdelloid rotifers capture additional ORFs shared between highly diverse retroelement types [PDF]

, 2017
© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Viruses 9 (2017): 78, doi:10.3390/v9040078.Rotifers of the class Bdelloidea, microscopic freshwater ...
Arkhipova, Irina R., Kenefick, Aubrey W., Rodriguez, Fernando   +2 more
core   +1 more source

Distinct Traits of Structural and Regulatory Evolutional Conservation of Human Genes with Specific Focus on Major Cancer Molecular Pathways

Cells, 2023
The evolution of protein-coding genes has both structural and regulatory components. The first can be assessed by measuring the ratio of non-synonymous to synonymous nucleotide substitutions.
Galina Zakharova, Alexander Modestov, Polina Pugacheva, Rijalda Mekic, Ekaterina Savina, Anastasia Guryanova, Anastasia Rachkova, Semyon Yakushov, Andrei Alimov, Elizaveta Kulaeva, Elena Fedoseeva, Artem Kleyman, Kirill Vasin, Victor Tkachev, Andrew Garazha, Marina Sekacheva, Maria Suntsova, Maksim Sorokin, Anton Buzdin, Marianna A. Zolotovskaia   +19 more
doaj   +1 more source

Endonuclease-containing Penelope retrotransposons in the bdelloid rotifer Adineta vaga exhibit unusual structural features and play a role in expansion of host gene families [PDF]

, 2013
© The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Mobile DNA 4 (2013): 19, doi:10.1186/1759-8753-4-19.Penelope-like elements (PLEs) are an enigmatic ...
Arkhipova, Irina R., Rodriguez, Fernando, Yushenova, Irina A.   +2 more
core   +2 more sources

Sequence Motif Analysis of PRDM9 and Short Inverted Repeats Suggests Their Contribution to Human Microdeletion and Microduplication Syndromes

BioMedInformatics, 2023
Holliday junctions are the first recognized templates of legitimate recombination. Their prime physiological role is meiotic homologous recombination, resulting in rearrangements of the genetic material.
Paris Ladias, Georgios S. Markopoulos, Charilaos Kostoulas, Ioanna Bouba, Agis Georgiou, Sofia Markoula, Ioannis Georgiou   +6 more
doaj   +1 more source

Linking Retroelements to Autoimmunity [PDF]

, 2008
In this issue, Stetson et al. (2008) report a mechanism by which host cells avert an autoimmune response to self-nucleic acids. They show that the nuclease Trex1 prevents the accumulation of DNA derived from endogenous retroelements that, if left ...
Bhoj, Vijay G., Chen, Zhijian J.
core   +1 more source

Domesticated LTR-Retrotransposon gag-Related Gene (Gagr) as a Member of the Stress Response Network in Drosophila

Life, 2022
The most important sources of new components of genomes are transposable elements, which can occupy more than half of the nucleotide sequence of the genome in higher eukaryotes.
Lidia Nefedova, Alexey Gigin, Alexander Kim   +2 more
doaj   +1 more source

Distinct composition and amplification dynamics of transposable elements in sacred lotus (Nelumbo nucifera Gaertn.) [PDF]

, 2022
Sacred lotus (Nelumbo nucifera Gaertn.) is a basal eudicot plant with a unique lifestyle, physiological features, and evolutionary characteristics. Here we report the unique profile of transposable elements (TEs) in the genome, using a manually curated ...
Cerbin, Stefan, Jiang, Ning, Li, Yang, Ou, Shujun, Sun, Yanni   +4 more
core   +1 more source

Differential Methylation of Syncytin-1 and 2 Distinguishes Fetal Growth Restriction from Physiologic Small for Gestational Age

American Journal of Perinatology Reports, 2018
Objective The retroviral genes encoding Syncytin-1 (SYN1) and Syncytin-2 (SYN2) are epigenetically regulated, uniquely expressed in the placenta and critical to placental function.
Sami P. Makaroun, Katherine P. Himes
doaj   +1 more source

Identification and characterization of abundant repetitive sequences in Eragrostis tef cv. Enatite genome [PDF]

, 2016
Multiple alignment of Ty1-copia RT paralog sequences identified in teff cv Enantite and Tsedey.
Bertolini, Edoardo, Gebre, Yohannes Gedamu, Pè, Mario Enrico, Zuccolo, Andrea   +3 more
core   +8 more sources