Results 1 to 10 of about 36,898 (116)

Retrotransposon-induced mosaicism in the neural genome [PDF]

Open Biology, 2018
Over the past decade, major discoveries in retrotransposon biology have depicted the neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 (L1) has been shown to be transcribed and mobilized in the brain ...
Gabriela-Oana Bodea, Geoffrey J Faulkner
exaly   +2 more sources

Exogenous Coronavirus Interacts With Endogenous Retrotransposon in Human Cells

Frontiers in Cellular and Infection Microbiology, 2021
There is an increased global outbreak of diseases caused by coronaviruses affecting respiratory tracts of birds and mammals. Recent dangerous coronaviruses are MERS-CoV, SARS-CoV, and SARS-CoV-2, causing respiratory illness and even failure of several ...
Ying Yin, Ying Yin, Ying Yin, Ying Yin, Xiao-zhao Liu, Xiao-zhao Liu, Xiao-zhao Liu, Ximiao He, Ximiao He, Ximiao He, Li-quan Zhou   +10 more
doaj   +1 more source

Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cells. [PDF]

PLoS Genetics, 2013
Retrotransposon sequences are positioned throughout the genome of almost every eukaryote that has been sequenced. As mobilization of these elements can have detrimental effects on the transcriptional regulation and stability of an organism's genome, most
Andrew T Schuster, Kavitha Sarvepalli, Eain A Murphy, Michelle S Longworth   +3 more
doaj   +1 more source

Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice. [PDF]

PLoS Genetics, 2017
Mammalian genomes harbor millions of retrotransposon copies, some of which are transpositionally active. In mouse prospermatogonia, PIWI-interacting small RNAs (piRNAs) combat retrotransposon activity to maintain the genomic integrity.
Kota Inoue, Kenji Ichiyanagi, Kei Fukuda, Michael Glinka, Hiroyuki Sasaki   +4 more
doaj   +1 more source

Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?

Biomedicines, 2021
Small extracellular vesicles (SEVs) such as exosomes are released by multiple cell types. Originally believed to be a mechanism for selectively removing unwanted cellular components, SEVs have received increased attention in recent years for their ...
Marilou H. Barrios, Alexandra L. Garnham, Andrew D. Foers, Lesley Cheng-Sim, Seth L. Masters, Ken C. Pang   +5 more
doaj   +1 more source

Low Sensitivity of Real Time PCRs Targeting Retrotransposon Sequences for the Detection of Schistosoma japonicum Complex DNA in Human Serum

Pathogens, 2021
While hybridization probe-based real-time PCR assays targeting highly repetitive multi-copy genome sequences for the diagnosis of S. mansoni complex or S.
Hagen Frickmann, Ulrike Loderstädt, Beatrice Nickel, Sven Poppert, Peter Odermatt, Somphou Sayasone, Marjan Van Esbroeck, Isabel Micalessi, Lieselotte Cnops, Poom Adisakwattana, Gérard Leboulle, Olfert Landt, Thorsten Thye, Egbert Tannich   +13 more
doaj   +1 more source

Comparative Repeat Profiling of Two Closely Related Conifers (Larix decidua and Larix kaempferi) Reveals High Genome Similarity With Only Few Fast-Evolving Satellite DNAs

Frontiers in Genetics, 2021
In eukaryotic genomes, cycles of repeat expansion and removal lead to large-scale genomic changes and propel organisms forward in evolution. However, in conifers, active repeat removal is thought to be limited, leading to expansions of their genomes ...
Tony Heitkam, Luise Schulte, Luise Schulte, Beatrice Weber, Susan Liedtke, Sarah Breitenbach, Anja Kögler, Kristin Morgenstern, Marie Brückner, Ute Tröber, Heino Wolf, Doris Krabel, Thomas Schmidt   +12 more
doaj   +1 more source

A molecular marker set combining a retrotransposon insertion and SSR polymorphisms is useful for assessing diversity in Vitis

OENO One, 2021
Molecular markers, based on DNA polymorphisms, are useful tools for identifying individuals, establishing phylogenetic relationships, managing collections of genetic material or assisting breeding.
Frederique Pelsy, Lucie Bevilacqua, Sophie Blanc, Didier Merdinoglu   +3 more
doaj   +1 more source

An Endogenous Retrovirus from Human Hookworm Encodes an Ancient Phlebovirus-Like Class II Envelope Fusion Protein

Proceedings, 2020
Within the parasitic nematode Ancylostoma ceylanicum, a ~20 million-year-old Bel/Pao LTR retrotransposon encodes an ancient viral class II envelope fusion protein termed Atlas Gc.
Monique Merchant, Carlos P. Mata, Yorgo Modis   +2 more
doaj   +1 more source

Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells.

PLoS Computational Biology, 2012
Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that silence retrotransposons in germ cells and pluripotent cells are important for limiting the ...
Judith Reichmann, James H Crichton, Monika J Madej, Mary Taggart, Philippe Gautier, Jose Luis Garcia-Perez, Richard R Meehan, Ian R Adams   +7 more
doaj   +1 more source