Exogenous Coronavirus Interacts With Endogenous Retrotransposon in Human Cells
Frontiers in Cellular and Infection Microbiology, 2021 There is an increased global outbreak of diseases caused by coronaviruses affecting respiratory tracts of birds and mammals. Recent dangerous coronaviruses are MERS-CoV, SARS-CoV, and SARS-CoV-2, causing respiratory illness and even failure of several ...
Ying Yin +10 more
doaj +2 more sources
Retrotransposon-induced mosaicism in the neural genome [PDF]
Open Biology, 2018 Over the past decade, major discoveries in retrotransposon biology have depicted the neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 (L1) has been shown to be transcribed and mobilized in the brain ...
Gabriela O. Bodea +2 more
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Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice. [PDF]
PLoS Genetics, 2017 Mammalian genomes harbor millions of retrotransposon copies, some of which are transpositionally active. In mouse prospermatogonia, PIWI-interacting small RNAs (piRNAs) combat retrotransposon activity to maintain the genomic integrity.
Kota Inoue +4 more
doaj +2 more sources
An age-of-allele test of neutrality for transposable element insertions [PDF]
Genetics. 2014 Feb;196(2):523-38, 2012 How natural selection acts to limit the proliferation of transposable elements (TEs) in genomes has been of interest to evolutionary biologists for many years. To describe TE dynamics in populations, many previous studies have used models of transposition-selection equilibrium that rely on the assumption of a constant rate of transposition.
Bergman, Casey M. +3 more
arxiv +4 more sources
Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells
Stem Cells International, 2018 Retrotransposons comprise a significant fraction of mammalian genome with unclear functions. Increasing evidence shows that they are not just remnants of ancient retroviruses but play important roles in multiple biological processes. Retrotransposons are
Ying Yin, Liquan Zhou, Shuiqiao Yuan
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Reverse Mutations in Pigmentation Induced by Sodium Azide in the IR64 Rice Variety [PDF]
Current Issues in Molecular BiologyPigmentation in rice is due mainly to the accumulation of anthocyanins. Five color mutant lines, AZ1701, AZ1702, AZ1711, AZ1714, and AZ1715, derived from the sodium azide mutagenesis on the non-pigmented IR64 variety, were applied to study inheritance ...
Hsian-Jun Chen +6 more
doaj +2 more sources
Repeats as global DNA methylation marker in bovine preimplantation embryos [PDF]
Czech Journal of Animal Science, 2017 DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a bisulfite sequencing based method aimed at repetitive
Wenwen Li, Ann Van Soom, Luc Peelman
doaj +4 more sources
The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]
, 1993 BUCHETON, A +3 more
core +2 more sources
Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription
Science, 2023 Non–long terminal repeat (non-LTR) retrotransposons, or long interspersed nuclear elements (LINEs), are an abundant class of eukaryotic transposons that insert into genomes by target-primed reverse transcription (TPRT). During TPRT, a target DNA sequence
M. E. Wilkinson +3 more
semanticscholar +1 more source
Loss of heterochromatin and retrotransposon silencing as determinants in oocyte aging
Aging Cell, 2022 Mammalian oocyte quality reduces with age. We show that prior to the occurrence of significant aneuploidy (9M in mouse), heterochromatin histone marks are lost, and oocyte maturation is impaired.
Peera Wasserzug-Pash +11 more
semanticscholar +1 more source