Results 11 to 20 of about 67,814 (281)

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

Nature Communications, 2011
Leonora Balaj, Xandra O Breakefield, Johan Skog   +2 more
exaly   +2 more sources

Retrotransposons and Telomeres

Biochemistry (Moscow), 2023
Abstract Transposable elements (TEs) comprise a significant part of eukaryotic genomes being a major source of genome instability and mutagenesis. Cellular defense systems suppress the TE expansion at all stages of their life cycle. Piwi proteins and Piwi-interacting RNAs (piRNAs) are key elements of the anti-transposon
Alla I, Kalmykova, Olesya A, Sokolova
openaire   +2 more sources

Loss of heterochromatin and retrotransposon silencing as determinants in oocyte aging

Aging Cell, 2022
Mammalian oocyte quality reduces with age. We show that prior to the occurrence of significant aneuploidy (9M in mouse), heterochromatin histone marks are lost, and oocyte maturation is impaired.
Peera Wasserzug-Pash, Rachel Rothman, E. Reich, Lital Zecharyahu, O. Schonberger, Yifat Weiss, N. Srebnik, Yaara Cohen-Hadad, A. Weintraub, I. Ben‐Ami, H. Holzer, Michael Klutstein   +11 more
semanticscholar   +1 more source

Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cells. [PDF]

PLoS Genetics, 2013
Retrotransposon sequences are positioned throughout the genome of almost every eukaryote that has been sequenced. As mobilization of these elements can have detrimental effects on the transcriptional regulation and stability of an organism's genome, most
Andrew T Schuster, Kavitha Sarvepalli, Eain A Murphy, Michelle S Longworth   +3 more
doaj   +1 more source

The retrotransposon R2 maintains Drosophila ribosomal DNA repeats

bioRxiv, 2021
Ribosomal DNA (rDNA) loci contain the hundreds of tandemly repeated copies of ribosomal RNA genes needed to support cellular viability. This repetitiveness makes it highly susceptible to copy number (CN) loss, threatening multi-generational maintenance ...
Jonathan O. Nelson, Alyssa Slicko, Y. Yamashita   +2 more
semanticscholar   +1 more source

Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?

Biomedicines, 2021
Small extracellular vesicles (SEVs) such as exosomes are released by multiple cell types. Originally believed to be a mechanism for selectively removing unwanted cellular components, SEVs have received increased attention in recent years for their ...
Marilou H. Barrios, Alexandra L. Garnham, Andrew D. Foers, Lesley Cheng-Sim, Seth L. Masters, Ken C. Pang   +5 more
doaj   +1 more source

Low Sensitivity of Real Time PCRs Targeting Retrotransposon Sequences for the Detection of Schistosoma japonicum Complex DNA in Human Serum

Pathogens, 2021
While hybridization probe-based real-time PCR assays targeting highly repetitive multi-copy genome sequences for the diagnosis of S. mansoni complex or S.
Hagen Frickmann, Ulrike Loderstädt, Beatrice Nickel, Sven Poppert, Peter Odermatt, Somphou Sayasone, Marjan Van Esbroeck, Isabel Micalessi, Lieselotte Cnops, Poom Adisakwattana, Gérard Leboulle, Olfert Landt, Thorsten Thye, Egbert Tannich   +13 more
doaj   +1 more source

Comparative Repeat Profiling of Two Closely Related Conifers (Larix decidua and Larix kaempferi) Reveals High Genome Similarity With Only Few Fast-Evolving Satellite DNAs

Frontiers in Genetics, 2021
In eukaryotic genomes, cycles of repeat expansion and removal lead to large-scale genomic changes and propel organisms forward in evolution. However, in conifers, active repeat removal is thought to be limited, leading to expansions of their genomes ...
Tony Heitkam, Luise Schulte, Luise Schulte, Beatrice Weber, Susan Liedtke, Sarah Breitenbach, Anja Kögler, Kristin Morgenstern, Marie Brückner, Ute Tröber, Heino Wolf, Doris Krabel, Thomas Schmidt   +12 more
doaj   +1 more source

A molecular marker set combining a retrotransposon insertion and SSR polymorphisms is useful for assessing diversity in Vitis

OENO One, 2021
Molecular markers, based on DNA polymorphisms, are useful tools for identifying individuals, establishing phylogenetic relationships, managing collections of genetic material or assisting breeding.
Frederique Pelsy, Lucie Bevilacqua, Sophie Blanc, Didier Merdinoglu   +3 more
doaj   +1 more source

An Endogenous Retrovirus from Human Hookworm Encodes an Ancient Phlebovirus-Like Class II Envelope Fusion Protein

Proceedings, 2020
Within the parasitic nematode Ancylostoma ceylanicum, a ~20 million-year-old Bel/Pao LTR retrotransposon encodes an ancient viral class II envelope fusion protein termed Atlas Gc.
Monique Merchant, Carlos P. Mata, Yorgo Modis   +2 more
doaj   +1 more source