Results 121 to 130 of about 161,769 (345)
detectEVE: Fast, Sensitive and Precise Detection of Endogenous Viral Elements in Genomic Data
ABSTRACT Endogenous viral elements (EVEs) are fragments of viral genomic material embedded within the host genome. Retroviruses contribute to the majority of EVEs because of their genomic integration during their life cycle; however, the latter can also arise from non‐retroviral RNA or DNA viruses, then collectively known as non‐retroviral (nr) EVEs ...
Nadja Brait+2 more
wiley +1 more source
Mapping m6A Sites on HIV-1 RNA Using Oligonucleotide LC-MS/MS
The biological significance of chemical modifications to the ribonucleic acid (RNA) of human immunodeficiency virus type-1 (HIV-1) has been recognized.
Alice Baek+8 more
doaj +1 more source
Drug hypersensitivity reactions specifically cutaenous adverse drug reaction (CADR) occur at higher rate in human immunodeficiency virus (HIV)- positive patients than general population and cause significant morbidity, in early era of antiretroviral ...
Vidyani Adiningtyas+2 more
doaj +1 more source
Retrovirus Vectors: Toward the Plentivirus?
Recombinant retroviral vectors based upon simple gammaretroviruses, complex lentiviruses, or potentially nonpathogenic spumaviruses represent relatively well characterized tools that are widely used for stable gene transfer. Different members of the Retroviridae family have developed distinct and potentially useful features related to their life cycle.
Melanie Galla+4 more
openaire +2 more sources
Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi+6 more
wiley +1 more source
Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H.+7 more
core
hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan
In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam+15 more
wiley +1 more source
La artritis y encefalitis Caprina (CAEV) puede presentar diferentes síntomas clínicos, siendo la artritis la más común. A fin de caracterizar la presencia de enfermedades en las majadas caprinas del noroeste argentino, se llevó a cabo una encuesta ...
DODERO AM+4 more
doaj +1 more source
Identification of nucleotide sequences which may encode the oncogenic capacity of avian retrovirus MC29 [PDF]
Diana Sheiness+2 more
openalex +1 more source
Engineered nanoparticles potentials in male reproduction
Abstract Background The escalating prevalence of fertility problems in the aging population necessitates a comprehensive exploration of contributing factors, extending beyond environmental concerns, work‐related stress, and unhealthy lifestyles. Among these, the rising incidence of testicular disorders emerges as a pivotal determinant of fertility ...
Feifei Zhao+8 more
wiley +1 more source