Results 101 to 110 of about 122,151 (262)

Ascending infection of Gardnerella spp. and compartmentalized inflammatory response in fetal–maternal interface organ‐on‐chip model

The Journal of Physiology, EarlyView.
Abstract figure legend The fetal–maternal interface organ‐on‐chip was used to investigate the ascending infection of Gardnerella spp. across the decidua (DEC), chorion trophoblast (CTC), amnion mesenchymal (AMC) and amnion epithelial (AEC) compartments over 48 h.
Mariana de Castro Silva, Jeniffer Sena Baptista Ferreira, Rafael Gomes Barnabé, Maria Eduarda Tesini Rocha, Laura Emi Yonezawa de Souza, Bruna Ribeiro de Andrade Ramos, Ramkumar Menon, Márcia Guimarães da Silva   +7 more
wiley   +1 more source

Hemophagocytic Syndrome in a Pancytopenic Simian Retrovirus–Infected Male Rhesus Macaque (Macaca mulatta)

, 2011
Hemophagocytic syndrome (HPS) is a macrophage hyperactivation disorder triggered by disrupted T–cell macrophage cytokine interaction. HPS has been reported in humans, dogs, cats, and cattle, and it is infrequent and poorly characterized in animals. A 16-
I. L. Bergin, T. M. Cotroneo, L. A. Colby   +2 more
core   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, Volume 101, Issue 6, Page 2471-2500, December 2026.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Mapping m⁶A Sites on HIV-1 RNA Using Oligonucleotide LC-MS/MS

Methods and Protocols
The biological significance of chemical modifications to the ribonucleic acid (RNA) of human immunodeficiency virus type-1 (HIV-1) has been recognized.
Alice Baek, Asif Rayhan, Ga-Eun Lee, Sarah Golconda, Hannah Yu, Shihyoung Kim, Patrick A. Limbach, Balasubrahmanyam Addepalli, Sanggu Kim   +8 more
doaj   +1 more source

Neuronal Overexpression of Glycogen Synthase Kinase‐3β Accelerates Age‐Related Glial, Vascular, and Inflammatory Remodeling of the Murine Dentate Gyrus

Glia, Volume 74, Issue 12, December 2026.
Aging induces layer‐specific changes in glial populations and vascular organization across the dentate gyrus. Neuronal GSK‐3β overexpression accelerates age‐related remodeling of the dentate gyrus neurogenic niche. GSK‐3β‐overexpressing mice show premature subgranular zone (SGZ) astrocyte loss, altered microglia and oligodendroglia, and vascular ...
Ana V. Prádanos‐Senén, Carla B. Rodríguez‐Moreno, María Llorens‐Martín   +2 more
wiley   +1 more source

Distinct Epigenetic Responses to Aging and Short‐Term High‐Fat Diet in Hepatic Lipid Metabolism Genes in Male and Female Mice

Liver International Communications, Volume 7, Issue 4, December 2026.
ABSTRACT Background and Aims Aging is associated with widespread epigenetic remodelling that contributes to metabolic alterations in the liver. High‐fat diet (HFD) represents a major environmental perturbation affecting hepatic metabolism, yet its specific impact on age‐associated epigenetic changes remains unclear.
Annalena Frank, Sascha Tierling, Beate Czepukojc, Sonja M. Kessler, Thomas Hentrich, Michael Kohlstedt, Johannes Haybaeck, Christoph Wittmann, Jessica Hoppstädter, Julia Schulze‐Hentrich, Alexandra K. Kiemer   +10 more
wiley   +1 more source

Before the Trial: Taxonomic Inference, AIDS, and the Limits of Evidence Appraisal

Journal of Evaluation in Clinical Practice, Volume 32, Issue 8, December 2026.
ABSTRACT Rationale Evidence‐based medicine (EBM) was founded to inform decisions about the care of individual patients. Its most developed appraisal tools, however, are calibrated primarily to the reliability of estimates produced within already constituted reference classes.
Frederick Arthur
wiley   +1 more source

Transmissible Retrovirus in Epstein-Burr Virus-Producer B95-8 Cells

, 1995
Epstein-Burr virus (EBV) released from the B95-8 marmoset cell line has served as a prototype for biologic and biochemical studies of EBV. Here we identify and characterize a retrovirus carried by many cultures of B95-8 cells.
Sun, Ren, Kushnaryov, Vladimir M., Miller, George, Grogan, Elizabeth, Grossberg, Sidney E., Bykovsky, Albert F., Shedd, Duane   +6 more
core   +1 more source

The Retrovirus Capsid Core

, 2018
The retrovirus capsid core is a metastable structure that disassembles during the early phase of viral infection after membrane fusion. The core is intact and permeable to essential nucleotides during reverse transcription, but it undergoes disassembly for nuclear entry and genome integration.
Zhang, Wei, Mendonça, Luiza M., Mansky, Louis M.   +2 more
openaire   +3 more sources

TMEM55B Maintains Lysosomal Homeostasis and Promotes ER–Lysosome Calcium Signaling

Traffic, Volume 27, Issue 4, December 2026.
Hypothetical model: The lysosomal protein TMEM55B interacts with an ER protein complex containing Protrudin and PDZD8 at ER–lysosome membrane contact sites, and also acts to stabilize v‐ATPase in lysosomes. Through these interactions, TMEM55B contributes to the maintenance of luminal homeostasis, including lysosomal acidification and regulates ER ...
Nagi Mukae, Honoka Maki, Michiko Shirane
wiley   +1 more source