Results 61 to 70 of about 134,326 (264)

Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain [PDF]

, 2023
Fumitoshi Ishino, Johbu Itoh, Masahito Irie, Ayumi Matsuzawa, Mie Naruse, Toru Suzuki, Yuichi Hiraoka, Tomoko Kaneko‐Ishino   +7 more
openalex   +1 more source

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo

Journal of Immunology, 2014
Tetherin/BST-2 is a host restriction factor that could directly inhibit retroviral particle release by tethering nascent virions to the plasma membrane. However, the immunological impact of Tetherin during retrovirus infection remains unknown.
Sam X Li, Bradley S. Barrett, Karl J. Heilman, Ronald J Messer, Rachel A. Liberatore, P. Bieniasz, G. Kassiotis, K. Hasenkrug, M. Santiago   +8 more
semanticscholar   +1 more source

The Epidemiology of Koala Retrovirus

Journal of Veterinary Epidemiology, 2011
A novel Gammaretrovirus, named Koala retrovirus (KoRV) was identified in koalas in 2000. Subsequent testing has shown that KoRV appears to be widespread throughout the wild koala population in Australia. KoRV is apparently unique in that it is the only known example of an exogenous retrovirus which is actively undergoing the process of endogenisation ...
Simmons, Greg, Young, Paul, McKee, Jeff, Meers, Joanne, Mizuno, Tetsuo   +4 more
openaire   +4 more sources

Prevention of retrovirus-induced neurological disease by infection with a nonneuropathogenic retrovirus

Virology, 1995
Perinatal infection of susceptible mice with the neurotropic retrovirus CasBrE leads to a noninflammatory spongiform degeneration of the central nervous system with a long incubation period of up to 1 year. Virus replication in infected animals can be suppressed by administration of antiviral antibodies, cytotoxic T cells, or by AZT treatment, which ...
Czub, Markus, McAtee, Frank J., Czub, Stefanie, Lynch, William P., Portis, John L.   +4 more
openaire   +2 more sources

Mammalian fatty acid synthase: a commonly used viral host dependency factor and a putative target for host-targeted broad-spectrum antiviral therapeutic development

mBio
Viruses regulate host processes to create cellular environments favorable to viral replication. At least 27 viruses that infect humans require host fatty acid synthase (FASN)-dependent de novo fatty acid biosynthesis, including viruses from the ...
Paola N. Loperena González, Krithika P. Karthigeyan, Jacqueline Corry, Anurup Krishna, Ben Hackenberg, Beatriz Sierra, Jesse J. Kwiek   +6 more
doaj   +1 more source

The Dynamic Interplay between HIV-1, SAMHD1, and the Innate Antiviral Response

Frontiers in Immunology, 2017
The innate immune response constitutes the first cellular line of defense against initial HIV-1 infection. Immune cells sense invading virus and trigger signaling cascades that induce antiviral defenses to control or eliminate infection.
Jenna M. Antonucci, Corine St. Gelais, Li Wu   +2 more
doaj   +1 more source

Stable cell line generation via retrovirus v1 [PDF]

, 2023
Dan Tudorica
openalex   +1 more source

Molecular Aspects of HTLV-1 Entry: Functional Domains of the HTLV-1 Surface Subunit (SU) and Their Relationships to the Entry Receptors

Viruses, 2011
The initial step in retroviral infection involves specific interactions between viral envelope proteins (Env) and specific receptors on the surface of target cells. For many years, little was known about the entry receptors for HTLV-1.
Sophie Lambert, Manuella Bouttier, Laurence Bénit, Frank W. Ruscetti, Olivier Hermine, Claudine Pique, Kathryn S. Jones   +6 more
doaj   +1 more source

Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs [PDF]

, 1991
FG Schuening, K Kawahara, A. Dusty Miller, R To, Sondra Goehle, Deborah C. Stewart, K Mullally, L Fisher, TC Graham, FR Appelbaum   +9 more
openalex   +1 more source

Herpes Simplex 2 Virus Depletes Cells of DEAD-Box Helicase 3 Protein by Packaging It into Virions

Viruses
Human DEAD-box helicase 3 (DDX3) is a multifunctional RNA helicase implicated in mRNA unwinding and the regulation of gene expression. While DDX3 has been extensively studied in the context of RNA virus replication, its role in DNA virus replication ...
Carmen Rita Piazza, Giulia Lottini, Paola Quaranta, Paola Perrera, Fabio Filippini, Michele Lai, Cristina Di Primio, Giulia Freer, Mauro Pistello   +8 more
doaj   +1 more source