Results 61 to 70 of about 122,151 (262)

Emerging Role of LY6E in Virus–Host Interactions

Viruses, 2019
As a canonical lymphocyte antigen-6/urokinase-type plasminogen activator receptor Ly6/uPAR family protein, lymphocyte antigen 6 complex, locus E (LY6E), plays important roles in immunological regulation, T cell physiology, and oncogenesis.
Jingyou Yu, Shan-Lu Liu
doaj   +1 more source

The Inhibition of HIV-1 Entry Imposed by Interferon Inducible Transmembrane Proteins Is Independent of Co-Receptor Usage

Viruses, 2018
Interferon inducible transmembrane proteins (IFITMs) are one of several IFN-stimulated genes (ISGs) that restrict entry of enveloped viruses, including flaviviruses, filoviruses and retroviruses.
Jingyou Yu, Shan-Lu Liu
doaj   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Preface to the Second Koala Retrovirus Workshop online 25–27 May 2021. In Proceedings of the Second Koala Retrovirus Workshop

, 2023
In 2013, the first Koala Retrovirus Workshop was held in San Diego, bringing together biology and veterinary specialists to assess and discuss the state of knowledge on koala retrovirus (KoRV) and to form professional bridges and networks.
Greenwood, Alex, Higgins, Damien, Singleton, Cora, Alquezar, David   +3 more
core   +1 more source

Koala retrovirus and neoplasia: correlation and underlying mechanisms [PDF]

The koala retrovirus, KoRV, is one of the few models for understanding the health consequences of retroviral colonization of the germline. Such colonization events transition exogenous infectious retroviruses to Mendelian traits or endogenous ...
Greenwood, Alex D., Tarlinton, Rachael
core   +3 more sources

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

The Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source

Human Retrovirus Codon Usage from tRNA Point of View: Therapeutic Insights

, 2013
The purpose of this study was to investigate the balance between transfer ribonucleic acid (tRNA) supply and demand in retrovirus-infected cells, seeking the best targets for antiretroviral therapy based on the hypothetical tRNA Inhibition Therapy (TRIT).
Vagner S. Fonseca, Diego Frias, Joana P. Monteiro-Cunha, Castro Filho, Bernardo Galvão, Tulio de Oliveira, Fonseca, Vagner S, Bernardo Galvao-Castro, Aline C. Mota-Miranda, Mota-Miranda, Aline Cristina Andrade, Oliveira, Tulio de, Cunha, Joana Paixão Monteiro, Fonseca, Vagner de Souza, Frias, Diego, Luiz C. J. Alcantara, Monteiro-Cunha, Joana Paixão, Alcantara, Luiz Carlos Júnior, Miranda, Aline Cristina Andrade Mota   +16 more
core   +1 more source

YTHDF1 and YTHDC1 m6A reader proteins regulate HTLV-1 tax and hbz activity

Journal of Virology
Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus responsible for adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a progressive neurodegenerative disease.
Emily M. King, Amanda Midkiff, Karsyn McClain, Sanggu Kim, Amanda R. Panfil   +4 more
doaj   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Patogenesi e peristenza delle infezioni da Retrovirus: aspetti di patologia comparata

, 2006
I Retrovirus, in grado di infettare numerosi esseri viventi come i pesci, gli uccelli ed i mammiferi incluso l’uomo, causano un’ampia gamma di patologie tra cui neoplasie, immunodeficienza, disordini neurologici e malattie sistemiche caratterizzate da ...
POLI, ALESSANDRO
core