Results 71 to 80 of about 122,151 (262)

Haematology and biochemistry parameters for koalas (Phascolarctos cinereus) on Raymond Island, Victoria: use of point‐of‐care analysers

Australian Veterinary Journal, EarlyView.
Biochemistry and haematology analytes can provide information on the health status of individual animals or populations in direct comparison to expected values or reference intervals developed using the same analysis methodology from a healthy reference population of the target species. Point‐of‐care analysers are increasingly used in the assessment of
RA Jelic, VSA Mella, N Courtman, JF Hammer, MB Krockenberger   +4 more
wiley   +1 more source

Multiple sclerosis-associated retrovirus and related human endogenous retrovirus-W in patients with multiple sclerosis: A literature review

, 2013
Human endogenous retrovirus-W and the closely related multiple sclerosis-associated retrovirus have been associated with neuro-inflammatory diseases including multiple sclerosis.
Matsha, Tandi, Matsha, Tandi Edith, Erasmus, Rajiv T, Hon, Gloudina Mary, Hon, Gloudina M   +4 more
core   +1 more source

Retrovirus-mediated gene transfer to cystic fibrosis airway epithelial cells: effect of selectable marker sequences on long-term expression [PDF]

, 1993
Retrovirus-mediated gene transfer offers the potential for stable long-term expression of transduced genes in host cells subsequent to integration of vector DNA into the host genome.
Richard C. Boucher, Boucher, Richard C., Johnson, Larry G., Larry G. Johnson, Olsen, John C., John C. Olsen, Ronald Swanstrom, Moore, Karen L., Karen L. Moore, Swanstrom, Ronald, Mabel L. Wong-Sun, Wong-sun, Mabel L.   +11 more
core   +1 more source

Human APOBEC3G suppresses homologous recombination and LIG4‐independent end joining in DNA double‐strand break repair

The FEBS Journal, EarlyView.
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito, Miori Murayama, Usaki Arai, Sekifumi Akatsu, Ami Yamamoto, Misaki Kadoguchi, Noritaka Adachi   +6 more
wiley   +1 more source

Multiple Sclerosis and Viruses: « Liaisons Dangereuses ». [PDF]

Rev Med Virol
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Plavina S, Malakovska D, Kalnina J, Trapina I, Leonova E, Habib M, Schifmann S, Paramonovs J, Sjakste N, Vassetzky Y, Drouet E, Paramonova N.   +11 more
europepmc   +2 more sources

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

Supplementary Data from SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy

, 2022
Supplementary Data from SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during ...
Dong Pan (1835707), Chuan-Yuan Li (14956853), Fang Li (41162), Xuhui Bao (6753419), Mengjie Hu (740819), Meng Jiao (14956850)   +5 more
core   +1 more source

Mammalian fatty acid synthase: a commonly used viral host dependency factor and a putative target for host-targeted broad-spectrum antiviral therapeutic development

mBio
Viruses regulate host processes to create cellular environments favorable to viral replication. At least 27 viruses that infect humans require host fatty acid synthase (FASN)-dependent de novo fatty acid biosynthesis, including viruses from the ...
Paola N. Loperena González, Krithika P. Karthigeyan, Jacqueline Corry, Anurup Krishna, Ben Hackenberg, Beatriz Sierra, Jesse J. Kwiek   +6 more
doaj   +1 more source

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

The FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro, Aurore Dougé, Klara Krpina, Lea‐Marie Schmitz, Christopher Forcados, Fatemeh Kaveh, Andrea Estrella Arias‐Díaz, Pascal Gelebart, Emmet McCormack, Renata Stripecke, Miguel Abal, Ben Davidson, Else Marit Inderberg, Sébastien Wälchli   +13 more
wiley   +1 more source

Phosphonoformate selective inhibition of murine retrovirus replication in vitro.

, 1982
Phosphonoformate selective inhibition of murine retrovirus replication in ...
RAFFANTI S. P, CARLONI G., VARNIER, OLIVIERO, REPETTO C. M   +3 more
core   +1 more source