Results 211 to 220 of about 120,627 (303)

Osteoarthritis: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 6, Issue 8, August 2025.
A schematic illustration of the pathogenesis and emerging therapeutic strategies for OA, including: risk factors and molecular mechanisms of OA, joint changes between healthy and OA conditions, and current emerging therapeutic approaches for OA. Abbreviations: IA: intra‐articular injection; EVs: extracellular vesicles. ABSTRACT Osteoarthritis (OA) is a
Wei Liu   +3 more
wiley   +1 more source

Correction: Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA damage and contributes to toxic side effects of chemotherapy. [PDF]

open access: yesCell Death Dis
Wang F   +16 more
europepmc   +1 more source

Genomic imprinting at a porcine ZNF locus via a canonical imprinting mechanism

open access: yesAnimal Genetics, Volume 56, Issue 4, August 2025.
Abstract Genomic imprinting causes parent‐of‐origin dependent gene expression, primarily driven by a subset of germline differentially methylated regions that function as imprinting control regions at promoter‐associated CpG islands. While these mechanisms have been investigated in depth in mice and humans, our understanding of the molecular basis of ...
Jinsoo Ahn   +5 more
wiley   +1 more source

Microbiome-Immune Interaction in Pulmonary Arterial Hypertension: What Have We Missed? [PDF]

open access: yesResearch (Wash D C)
Zhou X   +5 more
europepmc   +1 more source

Long‐acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re‐suppression outcomes in virally suppressed individuals living with HIV

open access: yesHIV Medicine, Volume 26, Issue 8, Page 1267-1288, August 2025.
Abstract Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking. Integrase inhibitor (INI) resistance may limit future therapy.
Kyle Ring   +4 more
wiley   +1 more source

Immune and vascular modulation by HERVs: the role of <i>CXCR1</i> and <i>IL18RAP</i> in dengue severity progression. [PDF]

open access: yesFront Immunol
Ferreira CS   +8 more
europepmc   +1 more source

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 282-307, July/August 2025.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari   +7 more
wiley   +1 more source

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