Results 81 to 90 of about 5,296 (150)

Expression Landscape and Circadian Regulation of lncRNAs in the Kidney

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Recent multi‐omics work shows that the diurnal rhythmicity of kidney function is associated with circadian oscillations in renal mRNA, protein and metabolite abundances. Yet circadian regulation of renal lncRNAs, which are emerging as important modulators of diverse (patho)physiological processes, remains largely unexplored. Here, we provide a
Leonore Wigger, Fanny Durussel, Muriel Auberson, Dmitri Firsov, Yohan Bignon   +4 more
wiley   +1 more source

Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization

Advanced Functional Materials, Volume 36, Issue 53, 2 July 2026.
We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat, Alexander Peraire‐Bueno, A. John Hart, Randall M. Erb   +3 more
wiley   +1 more source

Nuclear receptor protein: REV-ERB

Northern Clinics of Istanbul
REV-ERB α/β proteins play critical roles in circadian rhythm regulation and are considered to be specialized members of the nuclear receptor family. These so-called "orphan" proteins, whose endogenous ligands were initially unidentified, have become exogenously interferable through synthetic agents with the discovery of their endogenous ligands.
openaire   +2 more sources

P19 Cells as a Model for Studying the Circadian Clock in Stem Cells before and after Cell Differentiation

Journal of Circadian Rhythms, 2018
In mammals, circadian rhythmicity is sustained via a transcriptional/translational feedback loop referred to as the canonical molecular circadian clock.
Abdullah Mashhour, Zainab Al Mansour, Al Shaima Al Hallaj, Rizwan Ali, Thadeo Trivilegio, Mohamed Boudjelal   +5 more
doaj   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, Volume 102, Issue 4, Page 780-796, July/August 2026.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.

PLoS Biology, 2009
Heme is a ligand for the human nuclear receptors (NR) REV-ERBalpha and REV-ERBbeta, which are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose metabolism, and diseases such as diabetes, atherosclerosis ...
Keith I Pardee, Xiaohui Xu, Jeff Reinking, Anja Schuetz, Aiping Dong, Suya Liu, Rongguang Zhang, Jens Tiefenbach, Gilles Lajoie, Alexander N Plotnikov, Alexey Botchkarev, Henry M Krause, Aled Edwards   +12 more
doaj   +1 more source

Rev-erbs: Integrating Metabolism Around the Clock [PDF]

, 2016
Mammalian circadian and metabolic physiologies are intertwined, and the nuclear Rev-erbα is a key transcriptional link between them. Rev-erbα, and the highly related Rev-erbβ, are potent transcriptional repressors that are required for the function of the core mammalian molecular clock.
openaire   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases

Frontiers in Molecular Neuroscience, 2019
Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for homeostasis because disruption or misalignment of the intrinsic rhythms is associated with the onset
Hyo Kyeong Cha, Sooyoung Chung, Hye Young Lim, Jong-Wha Jung, Gi Hoon Son   +4 more
doaj   +1 more source

The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism

Diabetes and Vascular Disease Research, 2008
Circadian rhythms are normal variations in physiological processes that occur over the period of a day. These rhythms are essential for the organism since they allow anticipatory metabolic regulations to prepare for the up-coming feeding or rest period.
Hélène, Duez, Bart, Staels
openaire   +2 more sources