Results 91 to 100 of about 5,958,314 (335)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Touch screen assays of behavioural flexibility and error characteristics in Eastern grey squirrels (Sciurus carolinensis) [PDF]
, 2017 This is the final version of the article. Available from the publisher via the DOI in this record.Behavioural flexibility allows animals to adjust their behaviours according to changing environmental demands.
Chow, PKY, Lea, SEG, Leaver, LA, Wang, M
core +1 more source
Psychopharmacology, 2019 Dopamine D2-like receptors (D2R) are important drug targets in schizophrenia and Parkinson’s disease, but D2R ligands also cause cognitive inflexibility such as poor reversal learning. The specific role of D2R in reversal learning remains unclear.
J. Alsiö +11 more
semanticscholar +1 more source
Statistical Learning, Letter Reversals, and Reading [PDF]
Scientific Studies of Reading, 2014 Reversal errors play a prominent role in theories of reading disability. We examined reversal errors in the writing of letters by 5-6-year-old children. Of the 130 children, 92 had a history of difficulty in producing speech sounds, a risk factor for reading problems. Children were more likely to reverse letter forms that face left, such as 〈d〉 and 〈J〉,
Rebecca, Treiman +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
eLife, 2021 Inhibitory interneurons are believed to realize critical gating functions in cortical circuits, but it has been difficult to ascertain the content of gated information for well-characterized interneurons in primate cortex.
Kianoush Banaie Boroujeni +2 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2019 Dementia and cognitive decline have become worldwide health problems due to rapid growth of the aged population in many countries. We previously demonstrated that single or short-term administration of iso-α-acids, hop-derived bitter acids in beer ...
Tatsuhiro Ayabe, Rena Ohya, Yasuhisa Ano
doaj +1 more source
Frontiers in Pediatrics, 2020 Neonatal hypoxic-ischemic encephalopathy (HIE) remains a common problem world-wide for infants born at term. The impact of HIE on long-term outcomes, especially into adulthood, is not well-described.
Jessie R. Maxwell +11 more
doaj +1 more source
Does opportunistic testing bias cognitive performance in primates? Learning from drop-outs [PDF]
, 2019 Dropouts are a common issue in cognitive tests with non-human primates. One main reason for dropouts is that researchers often face a trade-off between obtaining a sufficiently large sample size and logistic restrictions, such as limited access to ...
Burkart, Judith M. +2 more
core +4 more sources