Results 251 to 260 of about 113,812 (280)

Cholesterol Efflux and Reverse Cholesterol Transport: Experimental Approaches

Current Medicinal Chemistry, 2016
Cholesterol efflux as a key event in reverse cholesterol transport (RCT) is considered now as both diagnostic tool and a promising target for the treatment of atherosclerosis. Radioactive in vitro cholesterol efflux assay (CEA) is the gold standard for determination of efflux at cellular level. Fluorescent tracers and stable isotope-labeled cholesterol
Alexander D. Dergunov, Evdokiya A. Garaeva, Dmitry Litvinov, Eugeny V. Savushkin   +3 more
openaire   +2 more sources

Reverse Cholesterol Transport

1989
Reverse cholesterol transport (RCT) is defined as transport of cholesterol from the periphery (e. g. the arterial wall) to the liver. This pathway is necessary, even in the presence of a strictly regulated cellular cholesterol synthesis and low-density lipoprotein (LDL) receptor-mediated endocytosis, because plasma cholesterol always accumulates in the
openaire   +2 more sources

Reverse cholesterol transport in familial hypercholesterolemia

Current Opinion in Lipidology, 2012
Familial hypercholesterolemia is characterized by a major elevation in circulating LDL-cholesterol levels, cholesterol deposition within the arterial wall and an increased risk of premature coronary artery disease. The reverse cholesterol transport (RCT) is now considered as a key process that protects against development of atherosclerosis.
openaire   +2 more sources

Drugs Affecting Reverse Cholesterol Transport

1993
Reverse cholesterol transport identifies a series of metabolic events resulting in the transport of excess cholesterol from peripheral tissues to the liver. High density lipoproteins (HDL) are the vehicle of cholesterol in this reverse transport, a function believed to explain the inverse correlation between plasma HDL levels and atherosclerosis.
G. Franceschini, G. Chiesa, L. Calabresi, C.R. Sirtori   +3 more
openaire   +3 more sources

Current concepts in reverse cholesterol transport

1990
The term reverse cholesterol transport first introduced by Glomset (1), identifies a process where there is net flux of cholesterol from the peripheral tissues to the liver. Because the liver is the single organ capable of significant cholesterol elimination from the body via bile acids peripheral tissues must utilize this system for carrying excess ...
Giancarlo Ghiselli, Roberto Musanti, Antonio M. Gotto   +2 more
openaire   +2 more sources

Incorporating Electrochemical Halide Oxidation into Drift‐Diffusion Models to Explain Performance Losses in Perovskite Solar Cells under Prolonged Reverse Bias

Advanced Energy Materials, 2021
Caleb C Boyd, Jay B Patel, Kevin A Bush
exaly  

Perovskite Photovoltaic Devices with Carbon‐Based Electrodes Withstanding Reverse‐Bias Voltages up to –9 V and Surpassing IEC 61215:2016 International Standard

Solar Rrl, 2022
Dmitry Bogachuk, David Martineau, Paul Gebhardt   +2 more
exaly  

Initial Stages of Reverse Transport of Cholesterol

1987
It can be estimated that in man a minimum of 1 g cholesterol day-1 must be removed from peripheral tissues and conveyed ultimately to the liver for processing and/or excretion. Only a small proportion of cells of extrahepatic tissues is in direct contact with blood plasma that is the main route of transport to the liver; most of those cells are ...
openaire   +2 more sources

Reverse-bias resilience of monolithic perovskite/silicon tandem solar cells

Joule, 2023
Stefaan De Wolf, Barry P Rand
exaly  

Rethinking Reverse Cholesterol Transport

Atherosclerosis Supplements, 2018
Antonio M. Gotto, Corina Rosales, Henry J. Pownall, Baiba K. Gillard   +3 more
openaire   +2 more sources