Friend Turns Foe: Transformation of Anti-Inflammatory HDL to Proinflammatory HDL during Acute-Phase Response [PDF]
, 2011 High-density lipoprotein (HDL) is a major carrier of cholesterol in the blood. Unlike other lipoproteins, physiological functions of HDL influence the cardiovascular system in favorable ways except when HDL is modified pathologically.
G, Hima Bindu +2 more
core +3 more sources
Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration [PDF]
, 2017 10.1194/jlr.M073684Journal of Lipid Research5891785 ...
Apte, Rajendra S. +10 more
core +2 more sources
World journal of gastroenterology, 2010 Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD.
J. Mark Brown, Ryan E. Temel
openaire +3 more sources
Understanding the Structure of High Density Lipoprotein [PDF]
, 2012 The high-density lipoprotein (HDL), the carrier of ‘good cholesterol’, transports cholesterol from periphery cells to liver for catabolism, a process termed reverse cholesterol transport.
Parshakov, Dmitriy, Tran, Kayla T.
core +1 more source
Effect of genotype on duodenal expression of nutrient transporter genes in dairy cows [PDF]
, 2013 peer-reviewedBackground Studies have shown clear differences between dairy breeds in their feed intake and production efficiencies. The duodenum is critical in the coordination of digestion and absorption of nutrients.
Buckley, Frank +3 more
core +1 more source
Reverse cholesterol transport revisited.
World journal of gastroenterology, 2010 Reverse cholesterol transport was originally described as the high-density lipoprotein-mediated cholesterol flux from the periphery via the hepatobiliary tract to the intestinal lumen, leading to fecal excretion. Since the introduction of reverse cholesterol transport in the 1970s, this pathway has been intensively investigated. In this topic highlight,
openaire +3 more sources
Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(delta/delta) mouse model of amyotrophic lateral sclerosis [PDF]
, 2010 Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo.
Bender, F.L.P. +9 more
core +4 more sources
Nuclear receptors in vascular biology [PDF]
, 2015 Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics.
A Chawla +56 more
core +2 more sources
Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes [PDF]
, 1994 Encapsulation of oligonucleotides in antibody-targeted liposomes (immunoliposomes) which bind to target cells permits intracellular delivery of the oligonucleotides.
Akhtar +42 more
core +1 more source
The Role of Macrophage Lipophagy in Reverse Cholesterol Transport
Endocrinology and Metabolism, 2017 Macrophage cholesterol efflux is a central step in reverse cholesterol transport, which helps to maintain cholesterol homeostasis and to reduce atherosclerosis. Lipophagy has recently been identified as a new step in cholesterol ester hydrolysis that regulates cholesterol efflux, since it mobilizes cholesterol from lipid droplets of macrophages via ...
Se-Jin Jeong, Mi-Ni Lee, Goo Taeg Oh
openaire +4 more sources