Results 81 to 90 of about 144,135 (296)
Frontiers in Physiology, 2018 Dyslipidemia (high concentrations of LDL-c and low concentrations of HDL-c) is a major cause of cardiovascular events, which are the leading cause of death in the world.
Leandro R. Marques +6 more
doaj +1 more source
Induction of obesity impairs reverse cholesterol transport in ob/ob mice. [PDF]
PLoS ONE, 2018 OBJECTIVES:Obesity is an independent risk factor for cardiovascular disease. Reverse cholesterol transport (RCT) is an important cardioprotective mechanism. This study aimed to investigate RCT changes in a murine model of obesity.
MyNgan Duong +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
eLife, 2017 Cholesterol partitions into accessible and sequestered pools in cell membranes. Here, we describe a new assay using fluorescently-tagged anthrolysin O, a cholesterol-binding bacterial toxin, to measure accessible cholesterol in human red blood cells ...
Rima S Chakrabarti +6 more
doaj +1 more source
Effect of genotype on duodenal expression of nutrient transporter genes in dairy cows [PDF]
, 2013 peer-reviewedBackground Studies have shown clear differences between dairy breeds in their feed intake and production efficiencies. The duodenum is critical in the coordination of digestion and absorption of nutrients.
Buckley, Frank +3 more
core +1 more source
Advanced Functional Materials, EarlyView.We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li +6 more
wiley +1 more source
Single session exercise stimulates formation of preβ1-HDL in leg muscle
Journal of Lipid Research, 2003 Physical activity can raise the level of circulating HDL cholesterol. Preβ1-HDL is thought to be either the initial acceptor of cellular cholesterol or virtually the first particle in the pathway of the formation of HDL from apolipoprotein A-I and ...
Dmitri Sviridov +4 more
doaj +1 more source
Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges
Advanced Functional Materials, EarlyView.Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley +1 more source
Acrolein impairs the cholesterol transport functions of high density lipoproteins.
PLoS ONE, 2015 High density lipoproteins (HDL) are considered athero-protective, primarily due to their role in reverse cholesterol transport, where they transport cholesterol from peripheral tissues to the liver for excretion.
Alexandra C Chadwick +7 more
doaj +1 more source
Future Therapeutic Directions in Reverse Cholesterol Transport [PDF]
Current Atherosclerosis Reports, 2010 Despite a robust inverse association between high-density lipoprotein (HDL) cholesterol levels and atherosclerotic cardiovascular disease, the development of new therapies based on pharmacologic enhancement of HDL metabolism has proven challenging. Emerging evidence suggests that static measurement of HDL levels has inherent limitations as a surrogate ...
Amit V, Khera, Daniel J, Rader
openaire +2 more sources