Rescue of bovine ephemeral fever virus through reverse genetics, but inability to propagate. [PDF]
Jasmeen P +6 more
europepmc +1 more source
Plasmid-Based Reverse Genetics System Enabling One-Step Generation of Genotype 3 Hepatitis E Virus. [PDF]
Kobayashi T +4 more
europepmc +1 more source
Establishment of a reverse genetics system for an epidemic strain of porcine rotavirus JXAY01 type G5P[23]I12. [PDF]
Liu C +6 more
europepmc +1 more source
Investigating the reassortment potential and pathogenicity of the S segment in Akabane virus using a reverse genetics system. [PDF]
Na EJ, Jeong CG, Chae SB, Oem JK.
europepmc +1 more source
Design and construction of a fast synthetic modified vaccinia virus Ankara reverse genetics system for advancing vaccine development. [PDF]
Gao Z +11 more
europepmc +1 more source
Generation of Simian Rotavirus Reassortants with Diverse VP4 and VP7 Genes Using Reverse Genetics.
Johne, Reimar +6 more
core
Reverse Genetics of Filoviruses
Reverse genetics systems are used for the generation of recombinant viruses. For filoviruses, this technology has been available for more than 15 years and has been used to investigate questions regarding the molecular biology, pathogenicity, and host adaptation determinants of these viruses.
Thomas, Hoenen +4 more
openaire +3 more sources
Reverse Genetics Systems for Filoviruses
Filoviruses are causative agents of severe hemorrhagic fevers with high case fatality rates in humans. For studies of virus biology and the subsequent development of countermeasures, reverse genetic systems, and especially those facilitating the generation of recombinant filoviruses, are indispensable.
Bianca S, Bodmer, Thomas, Hoenen
openaire +3 more sources
Reverse Genetics Systems for Filoviruses
Filoviruses are among the most pathogenic viruses known to man. Reverse genetics systems, in particular full-length clone systems, allow the generation of recombinant filoviruses, which can be used to study virus biology, but also for applied uses such as screening for countermeasures.
Thomas, Hoenen, Heinz, Feldmann
openaire +3 more sources
CRISPR: a versatile tool for both forward and reverse genetics research
Human genetics research employs the two opposing approaches of forward and reverse genetics. While forward genetics identifies and links a mutation to an observed disease etiology, reverse genetics induces mutations in model organisms to study their role
Mhamed Grati +2 more
exaly +2 more sources

