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Re-Examining Rotavirus Innate Immune Evasion: Potential Applications of the Reverse Genetics System
Rotaviruses represent one of the most successful pathogens in the world, with high infectivity and efficient transmission between the young of many animal species, including humans.
Avan Antia +2 more
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Marburg Virus Reverse Genetics Systems
The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
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Reverse genetics of rotavirus [PDF]
The genetics of viruses are determined by mutations of their nucleic acid. Mutations can occur spontaneously or be produced by physical or chemical means: for example, the application of different temperatures or mutagens (such as hydroxylamine, nitrous acid, or alkylating agents) that alter the nucleic acid.
openaire +2 more sources
Recent advances in Reovirales viruses reverse genetics research
Reovirales are segmented double-strand RNA viruses with a broad host range that pose a serious threat to human and animal health. However, there are numerous viral species within the Reovirales, some of which have lagged behind other RNA viruses in the ...
Xinyu Zhang, Feng Wen
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Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa +5 more
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Cytokines, reverse genetics and anti-cytokine therapy
Cytokines comprise the molecular language of communication between the cells, which is needed to maintain the homeostatic functions of the body (including the immune system) and mediate various diseases.
M. S. Drutskaya +9 more
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Reverse Genetics for Double-Stranded RNA Viruses
Resumen en inglès, ver archivo ...
H. Attoui +3 more
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Advantages, disadvantages and research progress on strategies for screening and identifying functional genes [PDF]
The screening and identification of functional genes is a key step to deeply understand various biological phenotypes. Forward genetics including traditional genetics, genome-wide association analysis, the comparison of gene expression profiles and ...
LIU Xu, CHANG De, WANG Jun-feng
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Canine adenoviruses (CAdVs) are divided into pathotypes CAdV1 and CAdV2, which cause infectious hepatitis and laryngotracheitis in canid animals, respectively.
Hiromichi Matsugo +6 more
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Rabies is a dangerous zoonoticdisease that affects the central nervous system, causes encephalomyelitis and paralyses and Is almost invariably fatal.
M. I. Doronin +6 more
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