Results 41 to 50 of about 668,266 (290)

Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed. [PDF]

open access: yes, 2014
Coat colours and patterns are highly variable in cats and are determined mainly by several genes with Mendelian inheritance. A 2-bp deletion in agouti signalling protein (ASIP) is associated with melanism in domestic cats. Bengal cats are hybrids between
Davis, BW   +5 more
core   +1 more source

Single-Round Infectious Particle Production by DNA-Launched Infectious Clones of Bungowannah Pestivirus

open access: yesViruses, 2020
Reverse genetics systems are powerful tools for functional studies of viral genes or for vaccine development. Here, we established DNA-launched reverse genetics for the pestivirus Bungowannah virus (BuPV), where cDNA flanked by a hammerhead ribozyme ...
Anja Dalmann   +5 more
doaj   +1 more source

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
A Bridgen   +73 more
core   +3 more sources

Influenza reverse genetics: dissecting immunity and pathogenesis

open access: yes, 2014
Reverse genetics systems allow artificial generation of non-segmented and segmented negative-sense RNA viruses, like influenza viruses, entirely from cloned cDNA.
Evans, Justin G.   +2 more
core   +1 more source

Identification and Validation of EST-Derived Molecular Markers, TRAP and VNTRs, for Banana Research [PDF]

open access: yes, 2011
The advent of high-throughput sequencing technology has generated abundant information on DNA sequences for the genomes of many plant species. Expressed Sequence Tags (ESTs), which are unique DNA sequences derived from a cDNA library and therefore ...
Ferreira, C.F.   +6 more
core   +2 more sources

Targeted Deletion and Inversion of Tandemly Arrayed Genes in Arabidopsis thaliana Using Zinc Finger Nucleases [PDF]

open access: yes, 2014
Tandemly arrayed genes (TAGs) or gene clusters are prevalent in higher eukaryotic genomes. For example, approximately 17% of genes are organized in tandem in the model plant Arabidopsis thaliana.
Baltes, Nicholas J.   +9 more
core   +1 more source

Epigenetics in Friedreich's ataxia: Challenges and opportunities for therapy [PDF]

open access: yes, 2013
Copyright © 2013 Chiranjeevi Sandi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Al-Mahdawi, S, Pook, MA, Sandi, C
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

One-Step Assembly of a Porcine Epidemic Diarrhea Virus Infectious cDNA Clone by Homologous Recombination in Yeast: Rapid Manipulation of Viral Genome With CRISPR/Cas9 Gene-Editing Technology

open access: yesFrontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV), a swine enteric coronavirus causing acute diarrhea in piglets, is one of the major threatens to the pork industry globally.
Yanyang Zhou   +10 more
doaj   +1 more source

Simple reverse genetics approach to elucidating the biosynthetic pathway of complex thiopeptide nocathiacin [PDF]

open access: yes, 2010
Biothythetic pathway of the most drugable thiopeptide nocathiacin has been elucidated by applying reverse genetics method based on its structural features.
Jing Deng   +4 more
core   +1 more source

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