Results 11 to 20 of about 1,866 (214)

Reverse genetics of rotavirus [PDF]

Proceedings of the National Academy of Sciences, 2017
The genetics of viruses are determined by mutations of their nucleic acid. Mutations can occur spontaneously or be produced by physical or chemical means: for example, the application of different temperatures or mutagens (such as hydroxylamine, nitrous acid, or alkylating agents) that alter the nucleic acid.
openaire   +2 more sources

Recent advances in Reovirales viruses reverse genetics research

Virus Research, 2022
Reovirales are segmented double-strand RNA viruses with a broad host range that pose a serious threat to human and animal health. However, there are numerous viral species within the Reovirales, some of which have lagged behind other RNA viruses in the ...
Xinyu Zhang, Feng Wen
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Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]

PLoS ONE, 2015
Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa, Pumaree Kanrai, Henning Petersen, Sherif Ibrahim, Silke Rautenschlein, Stephan Pleschka   +5 more
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Cytokines, reverse genetics and anti-cytokine therapy

Бюллетень сибирской медицины, 2019
Cytokines comprise the molecular language of communication between the cells, which is needed to maintain the homeostatic functions of the body (including the immune system) and mediate various diseases.
M. S. Drutskaya, E. O. Gubernatorova, E. A. Gorshkova, K.-S. N. Athertkhany, M. A. Nosenko, V. S. Gogoleva, O. A. Namakanova, R. V. Zvartsev, A. A. Kruglov, S. A. Nedospasov   +9 more
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Reverse Genetics for Double-Stranded RNA Viruses

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2009
Resumen en inglès, ver archivo ...
H. Attoui, F. Mohd Jaafar, S. Maan, P. P.C. Mertens   +3 more
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Advantages, disadvantages and research progress on strategies for screening and identifying functional genes [PDF]

Jichu yixue yu linchuang, 2022
The screening and identification of functional genes is a key step to deeply understand various biological phenotypes. Forward genetics including traditional genetics, genome-wide association analysis, the comparison of gene expression profiles and ...
LIU Xu, CHANG De, WANG Jun-feng
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Establishment of a Simple and Efficient Reverse Genetics System for Canine Adenoviruses Using Bacterial Artificial Chromosomes

Viruses, 2020
Canine adenoviruses (CAdVs) are divided into pathotypes CAdV1 and CAdV2, which cause infectious hepatitis and laryngotracheitis in canid animals, respectively.
Hiromichi Matsugo, Tomoya Kobayashi-Kitamura, Haruhiko Kamiki, Hiroho Ishida, Akiko Takenaka-Uema, Shin Murakami, Taisuke Horimoto   +6 more
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Modern approaches to production of safe and effective genetically modified rabies vaccines for animals

Ветеринария сегодня, 2023
Rabies is a dangerous zoonoticdisease that affects the central nervous system, causes encephalomyelitis and paralyses and Is almost invariably fatal.
M. I. Doronin, A. Mazloum, D. V. Mikhalishin, M. N. Mitrofanova, A. Yu. Sukharkov, V. V. Kiseleva, A. V. Sprygin   +6 more
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Rapid reconstruction of porcine reproductive and respiratory syndrome virus using synthetic DNA fragments

Computational and Structural Biotechnology Journal, 2021
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most challenging infectious disease of pig populations causing devastating economic loss to swine industry.
Julien Mélade, Géraldine Piorkowski, Hawa Sophia Bouzidi, Alain Medawar, Claudine Raffy, Xavier de Lamballerie, Antoine Nougairède   +6 more
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Highs and Lows in Calicivirus Reverse Genetics

Viruses
In virology, the term reverse genetics refers to a set of methodologies in which changes are introduced into the viral genome and their effects on the generation of infectious viral progeny and their phenotypic features are assessed.
Ángel L. Álvarez, Aroa Arboleya, Fábio A. Abade dos Santos, Alberto García-Manso, Inés Nicieza, Kevin P. Dalton, Francisco Parra, José M. Martín-Alonso   +7 more
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