Results 111 to 120 of about 399,425 (291)
Glia, Volume 71, Issue 2, Page 168-186, February 2023., 2023 Main Points Microglia become rapidly reactive in temporal lobe epilepsy (TLE). Microglia are major producers of TNFα during status epilepticus, which impairs astrocyte coupling and promotes gliosis. Depletion of microglia attenuates acute seizure activity in TLE.
Lukas Henning +10 more
wiley +1 more source
A Review of Electroanalytical Techniques for Determination of Anti-HIV Drugs
International Journal of Electrochemistry, 2011 Until now after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti-HIV compounds have been formally approved for clinical use in the treatment of ...
Burçin Bozal +2 more
doaj +1 more source
Thermolabile reverse transcriptase of a mammalian leukemia virus mutant temperature sensitive in its replication and sarcoma virus helper functions [PDF]
, 1975 Steven R. Tronick +3 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai +8 more
wiley +1 more source
Retinal regions shape human and murine Müller cell proteome profile and functionality
Glia, Volume 71, Issue 2, Page 391-414, February 2023., 2023 Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan +15 more
wiley +1 more source
Reversibility in space, time, and computation: the case of underwater acoustic communications [PDF]
arXiv, 2018 Time reversal of waves has been successfully used in communications, sensing and imaging for decades. The application in underwater acoustic communications is of our special interest, as it puts together a reversible process (allowing a reversible software or hardware realisation) and a reversible medium (allowing a reversible model of the environment).
arxiv
Reverse transcriptase mediated binding of primer tRNA to the viral genome [PDF]
, 1979 Alejandro Araya +2 more
openalex +1 more source
Advanced Science, EarlyView.This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao +16 more
wiley +1 more source
Study on immortalization of Mongolian sheep fibroblast cells
Animal BiotechnologyThis study aims to establish an immortalized fibroblast cell line from Mongolian sheep. Primary Mongolian sheep fibroblasts (SSF) were isolated using tissue explant and enzymatic digestion methods, followed by microscopic observation, growth curve ...
Bin. Liu +5 more
doaj +1 more source
Towards Reverse Engineering Reversible Logic [PDF]
arXiv, 2017 Reversible logic has two main properties. First, the number of inputs is equal to the number of outputs. Second, it implements a one-to-one mapping; i.e., one can reconstruct the inputs from the outputs. These properties enable its applications in building quantum computing architectures.
arxiv