Tenofovir and Doravirine Are Potential Reverse-Transcriptase Analogs in Combination with the New Reverse-Transcriptase Translocation Inhibitor (Islatravir) Among Treatment-Experienced Patients in Cameroon: Designing Future Treatment Strategies for Low- and Middle-Income Countries. [PDF]
Nka AD+26 more
europepmc +1 more source
Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
ABSTRACT Due to rapid global population growth and the resulting significant increase in food demand, the world is facing an epidemic of malnutrition. Although yield improvement remains one of the main targets of breeding programs, much attention is being paid to the nutritional aspects of crops, including nutrients and bioactive compounds that are ...
Maria Dellino+4 more
wiley +1 more source
De novo gene synthesis by an antiviral reverse transcriptase. [PDF]
Tang S+12 more
europepmc +1 more source
Authentic reverse transcriptase is coded by jockey, a mobile Drosophila element related to mammalian LINEs. [PDF]
В. А. Иванов+4 more
openalex +1 more source
ABSTRACT The objective of this study was to use a multi‐omics (i.e., gene expression quantification, metabolomics, and fatty acid [FA] profiling) approach to separate and authenticate beef from three different dietary groups. In this 2‐year study, Red Angus steers (n = 54) were randomly allocated to one of three treatments: (1) complex biodiverse ...
Lucas Krusinski+7 more
wiley +1 more source
Fundamental research on EV isolation, standardization and characterisation will bring about translational medical diagnostics and therapy. Abstract Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer nanoparticles secreted by most cells.
Karina P. De Sousa+5 more
wiley +1 more source
Identification of a novel small-molecule inhibitor of the HIV-1 reverse transcriptase activity with a non-nucleoside mode of action. [PDF]
Yu KL+11 more
europepmc +1 more source
Two independent retrons with highly diverse reverse transcriptases in Myxococcus xanthus. [PDF]
S Inouye, P. Herzer, Masayori Inouye
openalex +1 more source
Guidelines for Studying the Oxidative Stress Damage Model on Drosophila melanogaster
This guideline introduced Drosophila as a research model to summarize in detail the research methods of indicators that can characterize oxidative stress. It generally includes four aspects such as generation of ROS, damage caused by ROS, antioxidant defense, and cell stress repair and apoptosis.
Quanyong Wu
wiley +1 more source
Measuring the tail: Methods for poly(A) tail profiling
A development of the methods used to study the length and composition of poly(A) tails, uncovering the 3′‐end tailing as a much more complex and impactful process than previously thought. Abstract The 3′‐end poly(A) tail is an important and potent feature of most mRNA molecules that affects mRNA fate and translation efficiency.
Aleksandra Brouze+3 more
wiley +1 more source