Results 191 to 200 of about 1,758,180 (373)

Clinical Implications of Mutations at Reverse Transcriptase Codon 135 on Response to NNRTI-Based Therapy

, 2007
Harout Tossonian, Jesse D. Raffa, Jason Grebely, Mark Viljoen, Annabel Mead, Milan Khara, Mark McLean, Ashok Krishnamurthy, Stanley DeVlaming, Brian E. Conway   +9 more
openalex   +1 more source

Evidence for a Relief of Repression Mechanism for Activation of the Human Telomerase Reverse Transcriptase Promoter [PDF]

, 2003
Shuwen Wang, Jiyue Zhu
openalex   +1 more source

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

Advanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang, Zhi‐Xue Song, Si‐Ming Bu, Yi‐Mei Liu, Qing Li, Wen‐Xia Zhang, Xu‐Rong Sun, Xin Zhang, Yu‐Xuan Xiao, Di Bo, Xu‐Bin Miao, Chao Liu, Xin‐Hua Zhang, Lei Zheng, Hong‐Ye Zhao, Bao‐Lian Zhang, Wen Jia, Kui Chi, Yu Liu, Yong‐Bo Zhao, Bin Zheng, Dong Ma, Jin‐Kun Wen   +22 more
wiley   +1 more source

Effects of the Translocation Status of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on the Efficiency of Excision of Tenofovir

, 2007
Bruno Marchand, Kirsten White, John K Ly, Nicolas Margot, Ruth Wang, Martin J. McDermott, Michael D. Miller, Matthias Götte   +7 more
openalex   +1 more source

Essential roles of telomerase reverse transcriptase hTERT in cancer stemness and metastasis

FEBS Letters, 2018
Ricarda Hannen, J. Bartsch
semanticscholar   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Multiplexed Reverse Transcriptase PCR Assay for Identification of Viral Respiratory Pathogens at the Point of Care

, 2007
Sonia E. Létant, Josue I. Ortiz, Lance F. Bentley Tammero, James M. Birch, Robert W. Derlet, Stuart Cohen, Dannelle Manning, Mary T. McBride   +7 more
openalex   +2 more sources

Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase–Cas1 fusion protein

Science, 2016
Sukrit Silas, Georg Mohr, D. Sidote, Laura M. Markham, A. Sánchez-Amat, D. Bhaya, A. Lambowitz, A. Fire   +7 more
semanticscholar   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Quantification of CCR5 mRNA in Human Lymphocytes and Macrophages by Real-Time Reverse Transcriptase PCR Assay

, 2003
Jianping Lai, Jihong Yang, Steven D. Douglas, Xu Wang, Eric Riedel, Wen‐Zhe Ho   +5 more
openalex   +1 more source