Results 241 to 250 of about 570,932 (356)

Interactions with tRNA^Lys induce important structural changes in human immunodeficiency virus reverse transcriptase [PDF]

, 1990
Dominique Robert, Marie-Line Sallafranque-Andreola, Bruno B. Bordier, Leila Sarih‐Cottin, Laura Tarrago‐Litvak, Pierre Vincent Graves, Philip J. Barr, Michel Fournier, Simón Litvak   +8 more
openalex   +1 more source

Regulatory Role of FGL‐1 in Interorgan Communication by Controlling T Cell Homeostasis During the Onset of Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Autoimmunity occurs due to the tactics between pathogenic and regulatory factors in systemic organs. Although interorgan communication has been demonstrated in various diseases, the effects of the crosstalk between the immune system and other organs on autoimmune disease is unknown.
Kunihiro Otsuka, Aya Ushio, Ruka Nagao, Shigefumi Matsuzawa, Rieko Arakaki, Kazuki Fukuta, Yasuhiro Mouri, Takaaki Tsunematsu, Naozumi Ishimaru   +8 more
wiley   +1 more source

Tenofovir and Doravirine Are Potential Reverse-Transcriptase Analogs in Combination with the New Reverse-Transcriptase Translocation Inhibitor (Islatravir) Among Treatment-Experienced Patients in Cameroon: Designing Future Treatment Strategies for Low- and Middle-Income Countries. [PDF]

Viruses
Nka AD, Bouba Y, Tsapi Lontsi WR, Gouissi Anguechia DH, Teto G, Ka'e AC, Semengue ENJ, Ambe Chenwi C, Takou D, Forgwei L, Tekoh TA, Ngueko AMK, Fokou BB, Efakika Gabisa J, Tchouaket MCT, TognaPabo WL, Ayuk Ngwese DT, Njiki Bikoi J, Armenia D, Colizzi V, Yotebieng M, Ndembi N, Santoro MM, Ceccherini-Silberstein F, Perno CF, Ndjolo A, Fokam J.   +26 more
europepmc   +1 more source

Interactions Between Drug Resistance Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase

, 1994
B. A. Larder
openalex   +1 more source

A tolerogenic plasmid inhibits autoantibody production triggered by immunization with human peptidyl arginine deiminase 4.

Arthritis &Rheumatology, Accepted Article.
Objectives Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs).
Philippe P. Pagni, Vijetha Kumar, Nathalie C. Lambert, Eva Frison, Herve Luche, Marielle Mello, Magali Torres, Johnna D. Wesley, Matthias von Herrath, Jean Roudier, Isabelle Auger   +10 more
wiley   +1 more source

Development of 3D Cell-Based Fluorescent Reporter Assay for Screening of Drugs Downregulating Telomerase Reverse Transcriptase. [PDF]

Bioengineering (Basel)
Li Y, Zhang F, Qin Z, Yang ST.
europepmc   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

The truncated isoform of the receptor for hyaluronan-mediated motility (RHAMM^Δ163) modulates shelterin and telomerase reverse transcriptase transcription affecting telomerase activity. [PDF]

Front Aging
Basu K.
europepmc   +1 more source

Lamivudine and tenofovir pharmacokinetic variability in people with HIV in Papua New Guinea

British Journal of Clinical Pharmacology, EarlyView.
Aims Demographics and kidney function contribute to variability in lamivudine and tenofovir drug concentrations. The aim was to assess, for the first time, the pharmacokinetic variability of lamivudine and tenofovir in Papua New Guinean (PNG) HIV/AIDS patients.
Natália Bordin Andriguetti, Daniel Thomas Barratt, Joseph Tucci, Paul Pumuye, Andrew Alexander Somogyi   +4 more
wiley   +1 more source

Model‐based evaluation of the interaction between ritonavir‐boosted atazanavir and rifampicin in Ugandan adults with HIV

British Journal of Clinical Pharmacology, EarlyView.
Aim Concomitant treatment of tuberculosis (TB) and human immunodeficiency virus (HIV) is complicated by drug‐drug interactions (DDI). This analysis aimed to characterize the DDI between ritonavir‐boosted atazanavir (ATV/r) and rifampicin in plasma and peripheral blood mononuclear cells (PBMC).
Allan Kengo, Juan Eduardo Resendiz‐Galvan, Letisha Najjemba, Henry Mugerwa, Amedeo De Nicolò, Antonio D'Avolio, Shakir Atoyebi, Lubbe Wiesner, Elin M. Svensson, Catriona Waitt, Paolo Denti   +10 more
wiley   +1 more source