Results 261 to 270 of about 570,932 (356)

EZH2 negatively regulates IL‐8 expression in human nasal epithelial cells through its histone methyltransferase activity

open access: yesEye &ENT Research, EarlyView.
Abstract Background Chronic rhinosinusitis (CRS), characterized by persistent inflammation of the nasal and sinus mucosa, exhibits an escalating global prevalence and incidence. Interleukin‐8 (IL‐8), a key chemokine driving neutrophil recruitment, is implicated in CRS pathogenesis.
Yu Song   +4 more
wiley   +1 more source

Production of Reverse Transcriptase and DNA Polymerase in Bacterial Expression Systems. [PDF]

open access: yesBioengineering (Basel)
Hriňová K   +7 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Clinical impact of follow‐up endomyocardial biopsy in myocarditis during or after immune‐suppressive therapy

open access: yesESC Heart Failure, EarlyView.
Results and clinical implication of repeat endomyocardial biopsy (EMB). Abstract Aims While the diagnostic role of endomyocardial biopsy (EMB) in myocarditis is unquestioned, little is known about its indications and clinical value during long‐term follow‐up.
Anna Baritussio   +12 more
wiley   +1 more source

Adaptive immunity of type VI CRISPR-Cas systems associated with reverse transcriptase-Cas1 fusion proteins. [PDF]

open access: yesNucleic Acids Res
Molina-Sánchez MD   +7 more
europepmc   +1 more source

Protective Effects of Buckwheat and Isoquercitrin Against Noise‐Induced Hearing Loss in Mice: An Antioxidant Strategy Targeting the Nrf2/HO‐1 Pathway in Auditory Hair Cells

open access: yesFood Frontiers, EarlyView.
Isoquercitrin (IQ), a major bioactive compound in buckwheat (Fagopyrum esculentum Moench; BW), serves as a key mediator of the protective effects of BW against noise‐induced hearing loss (NIHL) by activating the Nrf2/HO‐1 signaling pathway, and oral administration of BW and IQ significantly attenuates oxidative stress and hair cell apoptosis through ...
Hojin Lee   +6 more
wiley   +1 more source

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