Results 271 to 280 of about 1,758,180 (373)

Peripheral blood telomerase activity and telomerase reverse transcriptase gene expression in psychiatric disorders: a systematic review and meta-analysis. [PDF]

Eur Psychiatry
Thurin J, Marie-Claire C, Etain B.
europepmc   +1 more source

Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure

, 2013
Mindy N. Carnahan, Kylee J. Veazey, Daria Müller, Joseph D. Tingling, Rajesh C. Miranda, Michael C. Golding   +5 more
openalex   +2 more sources

Human telomerase reverse transcriptase as a major therapeutic target in different cancer types [PDF]

, 2019
Zorawar Singh, Priya Khangotra
openalex   +1 more source

Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial.

Annals of Internal Medicine, 2014
J. Lennox, R. Landovitz, H. Ribaudo, I. Ofotokun, L. Na, C. Godfrey, D. Kuritzkes, M. Sagar, T. Brown, S. Cohn, G. McComsey, F. Aweeka, C. Fichtenbaum, R. Presti, S. Koletar, D. Haas, K. Patterson, C. Benson, B. Baugh, R. Leavitt, J. Rooney, D. Seekins, J. Currier   +22 more
semanticscholar   +1 more source

Orchestration of Skin Pathology in Cutaneous Lupus Erythematosus by HLA Class I Down‐Regulated Senescent Epidermal Basal Cells

Arthritis &Rheumatology, EarlyView.
Objective This study investigates the role of senescent epidermal basal cells in cutaneous lupus erythematosus (CLE) pathogenesis using skin samples from patients with CLE and a mouse model of systemic lupus erythematosus (SLE). Methods Cellular senescence profiling used datasets from the NCBI GEO database and Accelerating Medicines Partnership (AMP ...
Sena Yamamoto, Yuki Saito, Tsukasa Sato, Seina Nakano, Dain Kasseki, Ayaka Nagao, Norihiro Miura, Kentaro Nagaoka, Arisa Kita, Maki Miyajima, Shogo Ijima, Koji Taniguchi, Atsushi Niida, Takako S. Chikenji   +13 more
wiley   +1 more source

Structural basis for the evolution of a domesticated group II intron-like reverse transcriptase to function in host cell DNA repair. [PDF]

Proc Natl Acad Sci U S A
Park SK, Guo M, Stamos JL, Kim W, Lee S, Zhang YJ, Lambowitz AM.   +6 more
europepmc   +1 more source

Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma

Nature Communications, 2014
Barbara Heidenreich, E. Nagore, P. S. Rachakonda, Z. García-Casado, C. Requena, V. Traves, J. Becker, N. Soufir, K. Hemminki, K. Hemminki, Rajiv Kumar   +10 more
semanticscholar   +1 more source

A Tolerogenic Plasmid Inhibits Autoantibody Production Triggered by Immunization With Human Peptidyl Arginine Deiminase 4

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs). We have previously demonstrated that the human PAD4 (hPAD4) is
Philippe P. Pagni, Vijetha Kumar, Nathalie C. Lambert, Eva Frison, Herve Luche, Marielle Mello, Magali Torres, Johnna D. Wesley, Matthias von Herrath, Jean Roudier, Isabelle Auger   +10 more
wiley   +1 more source

Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine–thymine tracts

, 2002
Wenhui Zhang, Evguenia S. Svarovskaia, Rebekah Barr, Vinay K. Pathak   +3 more
openalex   +1 more source

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

British Journal of Clinical Pharmacology, EarlyView.
Aims To determine breastmilk concentrations of doravirine via PBPK modelling in combination with a clinical lactation study. As women living with HIV are not able to cease antiretroviral therapy during lactation, it is necessary to establish drug transfer into breastmilk to determine exposure of the infant to antiretroviral drugs and potential risk of ...
Lena van der Wekken‐Pas, David Burger, Rick Greupink, Angela Colbers   +3 more
wiley   +1 more source