Results 211 to 220 of about 266,159 (347)

Evaluation of the Antioxidant, Anticancer, and Antibacterial Activities of Flower and Leaf Extracts of Chrysanthemum indicum

ChemistryOpen, EarlyView.
The tested methanolic extract of Chrysanthemum indicum flower and leaf is a rich source of bioactive molecules with significant antioxidant activity at low doses, potential anticancer effects at lower concentrations, and antimicrobial activities against Gram‐positive and Gram‐negative species, which is consistent with the plant's traditional ...
Tarad Abalkhail, Noorah A. Alkubaisi, Ibrahim M. Aziz, Mashail Fahad Alsayed, Hissah Abdulrahman Alodaini, Amal Saad AL‐Shenifi, Mohamed A. Farrag   +6 more
wiley   +1 more source

Prolonged Measles Virus Shedding in Human Immunodeficiency Virus–Infected Children, Detected by Reverse Transcriptase–Polymerase Chain Reaction [PDF]

, 2001
Sallie R. Permar, William J. Moss, Judith J. Ryon, Mwaka Monze, Felicity Cutts, Thomas C. Quinn, Diane E. Griffin   +6 more
openalex   +1 more source

Anti‐Inflammatory/Antioxidant Features of Adipose Tissue Mesenchymal Stem Cells Conditioned Media for Doped TiO2 Nanoparticles in Induced Inflammation

ChemistryOpen, EarlyView.
The PI3K/AKT pathway is triggered when lipopolysaccharide (LPS) binds to TLR4 on the cell membrane. This causes the NF‐κB complex to get phosphorylated and IKB to degrade, allowing NF‐κB to go into the nucleus. Pro‐inflammatory genes including interleukin‐4 (IL‐4), IL‐6, and tumor necrosis factor α are triggered by this.
Ahmed A. Abd‐Rabou, Ahmed M. Youssef, Mohamed I. El‐Khonezy, Soheir E. Kotob, Mohamed S. Kishta   +4 more
wiley   +1 more source

Thiostrepton Suppresses the Progression of Rhabdomyosarcoma by Inhibiting the PI3K‐AKT Signaling Pathway

Pediatric Discovery, EarlyView.
The study establish TST as a multi‐mechanism PI3K‐AKT inhibitor for refractory RMS while validating Cmap‐driven drug repurposing for pediatric oncology. ABSTRACT Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma with 5‐year survival below 30% in high‐risk/metastatic cases, was investigated through integrated bioinformatics analysis (
Yu Wang, Peng Hong, Zhiqiang Gao, Wei Ma, Zaihong Hu, Jie Lin, Kongkong Cui, Qinlin Shi, Xiao‐Mao Tian, Guanghui Wei   +9 more
wiley   +1 more source

Analysis of multiple‐herbicide resistant Amaranthus palmeri populations from Spain points to an introduction of the eccDNA from America

Pest Management Science, EarlyView.
In this study, multiple herbicide resistant mechanisms have been confirmed in two Amaranthus palmeri populations from Spain that survived glyphosate‐ and ALS‐inhibitor herbicides. Our data suggest that the eccDNA and the mutations identified in the ALS gene are the result of an evolutionary event that occurred outside Spain.
Alfredo Manicardi, Germán Mora, André Lucas Simões Araujo, Todd A. Gaines, Jorge Lozano‐Juste, Joel Torra   +5 more
wiley   +1 more source

Immune priming of honey bees protects against a major microsporidian pathogen

Pest Management Science, EarlyView.
We immune‐primed honey bees at two developmental stages in the laboratory and the field with heat‐killed Nosema ceranae spores. When subsequently fed live spores, immune‐primed adults had lower infection levels. Abstract BACKGROUND Honey bees face significant threats from pathogens like Nosema ceranae, a microsporidian parasite that contributes to ...
James C. Nieh, Matthew Endler, Andrey Rubanov, Alexander Neskovic, Xianbing Xie, Honghong Li, Zachary Y. Huang   +6 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Diagnosis of Mucormycosis Using Frozen Section, Histopathology, Culture, and Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) Techniques: A Comparative Study. [PDF]

Cureus
Kiruthiga KG, Kulkarni A, Joshi A, Pradhan A, Naik S.   +4 more
europepmc   +1 more source

Epidemiology, Outcomes, and Associated Factors of Coronavirus Disease 2019 (COVID-19) Reverse Transcriptase Polymerase Chain Reaction-Confirmed Cases in the San Pedro Sula Metropolitan Area, Honduras. [PDF]

Clin Infect Dis, 2021
Zuniga-Moya JC, Norwood DA, Romero Reyes LE, Barrueto Saavedra E, Diaz R, Fajardo WC, Pineda A, Torres D, Barahona R, Leiva SO, Hernandez PX, Silva H, Leiva CR, Estrada L, Barahona-Campos A, Gordon A.   +15 more
europepmc   +1 more source