Results 71 to 80 of about 562,468 (202)

Rpf‐Toxo: A Preliminary Computationally Designed Dense Granule Antigen‐Based Multi‐Epitope Vaccine Against Toxoplasma gondii

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This graphical abstract summarizes the in silico design of the multi‐epitope vaccine candidate Rpf‐Toxo (Seq4) against Toxoplasma gondii. The workflow includes antigen selection, epitope mapping, vaccine construction, structural and immunological evaluation, toll‐like receptor‐4 docking, immune simulation, safety assessment, codon optimisation and ...
Mohamad Hosein Safari, Seyyed Amir Hosseini, Shadan Ghiabi, Shamim Ghiabi, Davood Siamian, Hamidreza Majidiani, Hamid Irannejad, Ali Asghari   +7 more
wiley   +1 more source

Selection of vaccine candidates for fish pasteurellosis using reverse vaccinology and an in vitro screening approach

, 2016
The advent of new technologies in recent years has revolutionized the methods by which pathogens are studied and at the same time it has provided new tools to design vaccines against infections for which vaccine development has so far been unsuccessful ...
Giulia Amagliani, MAGNANI, MAURO, Mauro Magnani, ANDREONI, FRANCESCA, Francesca Andreoni, AMAGLIANI, GIULIA   +5 more
core   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, Volume 179, Issue 1, Page 54-71, September 2026.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík, Mikolaj Adamek, Tomáš Korytář   +2 more
wiley   +1 more source

Computational Screening of Membrane Protein Epitopes for Vaccine Development Against Trypanosoma brucei 

Proceedings
Introduction: African trypanosomiasis is a fatal parasitic disease that affects both humans and animals [...]
Mariana Fochesato, Kayllany P. Santos, Maria E. L. Fernandes, Ytallo C. Sousa, Ygor Victor Ferreira Pinheiro, Leiz Maria Costa Véras   +5 more
doaj   +1 more source

Past and Present Vaccinations in Sweden

Acta Paediatrica, EarlyView.
Sven Arne Silfverdal
wiley   +1 more source

Reverse vaccinology assisted designing of multiepitope-based subunit vaccine against SARS-CoV-2

Infectious Diseases of Poverty, 2020
Background Coronavirus disease 2019 (COVID-19) linked with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause severe illness and life-threatening pneumonia in humans.
Muhammad Tahir ul Qamar, Farah Shahid, Sadia Aslam, Usman Ali Ashfaq, Sidra Aslam, Israr Fatima, Muhammad Mazhar Fareed, Ali Zohaib, Ling-Ling Chen   +8 more
doaj   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, Volume 13, Issue 46, 17 August 2026.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Genes Associated With Fracture Risk in Thoroughbred Horses Have Novel Roles in Osteogenesis

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Bone fractures in Thoroughbred racehorses are a major welfare problem. Genetic factors contribute to fracture risk. Cell models have previously identified 112 differentially expressed genes in bone‐forming osteoblasts derived from horses at high and low genetic risk of fracture. However, 42 of these genes have no published role in bone.
Amy C. Ross, Ellison S. Lumsden, Caroline Flood, Jayesh Dudhia, Androniki Psifidi, Deborah J. Guest   +5 more
wiley   +1 more source

Global vaccinology training : report from an ADVAC workshop

, 2019
: At a workshop on 7-8 November 2018 the leaders of 26 advanced vaccinology courses met to carry out an extensive review of the existing courses worldwide, in order to identify education gaps and future needs and discuss potential collaboration. The main
Lambert, Paul-Henri, Podda, Audino, Afaayo, Rachel, Comiadiere, Behazine, Pansier, Benedicte, Finn, Adam, Talbot, Keipp, Wouters, Ine, Asturias, Edwin, Arora, Narendra, Wang, Likui, Costa Clemens, Sue Ann, Mosina, Liudmila, Tipping, Jane, Muloiwa, Rudzani, Andersson, Lizzelott, Lynch, Julia Anne, Meric, Claude, Bose, Anuradha, Angele, Sandra, MacDonald, Noni, Kraehenbuhl, Jean-Pierre, Malande, Oliver Ombeva, Kane, Ndeye Coumba Toure, Dochez, Carine, Cutland, Clare, Gambillara Fonck, Veronica, Beal, Amanda Shortell, Ashfield, Rebecca, Tikoo, Suresh, Paul, Stephane, Scott, Anthony, Phalipon, Armelle, Duclos, Philippe, Kagina, Benjamin, van Damme, Pierre, Finan, Amy, Nohynek, Hanna, Koeck, Jean-Louis, Pattyn, Jade, Lindstrand, Ann, Martinez, Lindsay, Rodewald, Lance   +42 more
core