Results 81 to 90 of about 562,468 (202)

Table_1_A reverse vaccinology approach identifies putative vaccination targets in the zoonotic nematode Ascaris.xlsx

open access: yes, 2022
Ascariasis is the most prevalent helminthic disease affecting both humans and pigs and is caused by the roundworms Ascaris lumbricoides and Ascaris suum.
Martha Betson (132646)   +3 more
core   +1 more source

Immuno‐Informatics Design of Multi‐Epitope Vaccine Candidate Against Anaplasma phagocytophilum Using Major Surface Protein 4 (MSP‐4) Antigen

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Bovine anaplasmosis is an intracellular tick‐borne, non‐contagious disease caused by gram‐negative bacteria of the family Anaplasmataceae and order Rickettsia. Anaplasma phagocytophilum is the etiological agent for human granulocytic anaplasmosis associated with severe health implications in parts of Europe and the USA and ...
Samson Anjikwi Malgwi   +5 more
wiley   +1 more source

Computer Aided Biotechnology: from Immuno-informatics to Reverse Vaccinology [PDF]

open access: yes, 2008
Genome sequences from many organisms, including humans, have been completed, and high-throughput analyses have produced burgeoning volumes of 'omics' data. Bioinformatics is crucial for the management and analysis of such data and is increasingly used to
Raghava, G. P. S.   +19 more
core   +1 more source

High throughput genomic and proteomic technologies in the fight against infectious diseases

open access: yesJournal of Infection in Developing Countries, 2013
New technologies have shown significant promise in the fight against infectious diseases, with the discovery of novel molecular targets for in vitro diagnostics and the improved design of vaccines.
Alessandro Tanca   +3 more
doaj   +1 more source

System Theoretic Methods in Drug Discovery and Vaccine Formulation: Review and Perspectives

open access: yesDrugs and Drug Candidates
The methods utilized in the drug discovery pipeline routinely combine machine learning and deep learning algorithms to enhance the outputs. The generation of a drug target, through virtual screening and computational analysis of databases used for target
Ankita Sharma   +2 more
doaj   +1 more source

Reverse vaccinology based identification of anti- Rhipicephalus microplus vaccine candidates [PDF]

open access: yes, 2013
Thesis (PhD)--University of Pretoria, 2013.The rapid geographic expansion of the cattle tick species, Rhipicephalus microplus, as well as the introduction of diseases into previously unaffected areas and the increased incidence of acaricide resistance in

core   +1 more source

Immunoinformatics: Implications on Reverse Vaccinology

open access: yesImmunochemistry & Immunopathology, 2017
One area in which immunological studies have had most immediate and successful application is in the field of vaccination. Vaccines represent one of the greatest interventions in modern medicine [1]. Ever since Edward Jenner’s first use of a vaccine against smallpox in 1796, the use of vaccines has become indispensable to the eradication of disease [2].
openaire   +1 more source

Table_5_A reverse vaccinology approach identifies putative vaccination targets in the zoonotic nematode Ascaris.xlsx

open access: yes, 2022
Ascariasis is the most prevalent helminthic disease affecting both humans and pigs and is caused by the roundworms Ascaris lumbricoides and Ascaris suum.
Martha Betson (132646)   +3 more
core   +1 more source

Future Perspectives on the Application of Systems Biology and Generative Artificial Intelligence in the Design of Immunogenic Peptides for Vaccines

open access: yesVaccines
Peptide-based vaccines offer a modular and readily manufacturable platform for both prophylactic and therapeutic immunization. However, their broader translation has been constrained by the limited capacity to predict protective immunity directly from ...
José M. Pérez de la Lastra   +3 more
doaj   +1 more source

Design, Construction, and Efficacy of a Novel Multiepitope Chimeric Vaccine Against Lumpfish (Cyclopterus lumpus) Infection

open access: yesFishes
The development of effective vaccines is a critical step in effective disease management in aquaculture. This study introduces a novel Multiepitope Chimeric Vaccine (MCV) designed to enhance immunity in lumpfish against Vibrio anguillarum, Aeromonas ...
Joy Chukwu-Osazuwa   +8 more
doaj   +1 more source

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