Results 121 to 130 of about 1,341 (183)

2023 FDA TIDES (Peptides and Oligonucleotides) Harvest [PDF]

open access: yes
A total of nine TIDES (pepTIDES and oligonucleoTIDES) were approved by the FDA during 2023. The approved four oligonucleotide are indicated for various types of disorders, including amyotrophic lateral sclerosis, geographic atrophy, primary hyperoxaluria
Al Musaimi O   +3 more
core  

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM [PDF]

open access: yes
Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who are immunocompromised
Bassetti, Matteo   +9 more
core   +2 more sources

Innovative antifungal strategies to combat drug-resistant Candida auris: recent advances and clinical implications

open access: yesFrontiers in Cellular and Infection Microbiology
Candida auris is an invasive fungal pathogen recognized globally as a significant health threat due to its marked resistance to multiple classes of antifungal agents, including azoles, echinocandins, and polyenes.
Wei Du, Qihui Wang, Min Zhao
doaj   +1 more source

Candidemia: An Update on Epidemiology, Risk Factors, Diagnosis, Susceptibility, and Treatment

open access: yesPathogens
Candidemia is a highly prevalent invasive fungal infection caused primarily by C. albicans, C. parapsilosis, C. glabrata (currently Nakaseomyces glabratus), C. tropicalis, and C. krusei (currently Pichia kudriavzevii). Risk factors for the development of
Juan Pablo Cabrera-Guerrero   +7 more
doaj   +1 more source

Epidemiology, treatment options and outcome of invasive infections caused by Aspergillus section Usti [PDF]

open access: yes, 2020
Background. Aspergillus spp. of section Usti (A. ustus) represent a rare cause of invasive aspergillosis (IA). This multicenter study describes the epidemiology and outcome of A. ustus infections. Methods. Patients with A.
GLAMPEDAKIS, Emmanouil
core  

Exploring a Therapeutic Gold Mine:The Antifungal Potential of the Gold-Based Antirheumatic Drug Auranofin [PDF]

open access: yes
Human fungal infections comprise systemic mycoses as well as various skin diseases. Rising case numbers along with inefficient therapies and the appearance of drug-resistant strains unleashed a considerable health problem over the last years.
Biersack, Bernhard   +2 more
core   +1 more source

Title: Synergism between Fluconazole and Terminalia catappa Extract and its Use in the Treatment of Candida-infected Tenebrio molitor Larvae / Título: Sinergismo entre Fluconazol e o Extrato de Terminalia catappa e seu uso no tratamento de larvas de Tenebrio molitor infectadas com Candida [PDF]

open access: yes, 2020
The increase of Candida infections in the last few decades is alarming and the resistance development to antifungals, especially fluconazole, the most widely used drug for treatment, enhances the importance of these infections.
Andrade Monteiro, Cristina de   +7 more
core   +1 more source

FDA-Approved Antibacterials and Echinocandins [PDF]

open access: yes
Since 1955, a total of 12 peptide-based drugs with antimicrobial or antifungal properties have received approval from the Food and Drug Administration (FDA).
Al Musaimi O
core  

Candida Auris Features and its Treatment: Global Emergency [PDF]

open access: yes
Fungal pathogen Candida auris was identified in 2009, in Japan. Currently, it is identified in 5 continents, in more than 40 countries. Therefore, it is nowadays defined as critical priority pathogen.
Durán, Nelson   +2 more
core   +2 more sources

Update on therapeutic approaches for invasive fungal infections in adults

open access: yesTherapeutic Advances in Infectious Disease
Invasive fungal infections are increasingly encountered with the expansion of iatrogenic immunosuppression, including not only solid organ and hematopoietic stem cell transplant recipients but also patients with malignancies or autoimmune diseases ...
Catherine-Audrey Boutin, Me-Linh Luong
doaj   +1 more source

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