Results 61 to 70 of about 51,297 (183)

Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells

Frontiers in Pharmacology, 2019
20(S)-ginsenoside Rh2 (Rh2), a well-known protopanaxadiol-type ginsenoside from Panax ginseng has especially gained attention for its anticancer activities on various types of human cancer cells.
Ji Zhang, Weibo Li, Qiaoyun Yuan, Jing Zhou, Jianmei Zhang, Yufeng Cao, Guangbo Fu, Weicheng Hu   +7 more
doaj   +1 more source

Thermal and Photocatalytic Conversion of CO2 to Ethanol: Advances in Catalyst Design, Challenges, and Opportunities

ChemSusChem, Volume 19, Issue 12, 26 June 2026.
This review examines thermo‐ and photocatalytic routes for converting CO2 to ethanol and analyzes how metal alloying, promoters, supports, surface structure, and semiconductor design govern catalyst activity, selectivity, and stability. It integrates mechanistic insights from experimental and theoretical studies and identifies the main challenges and ...
Bryan Rocano‐Merchan, Alejandro Cañete‐Arché, Asier Agrelo‐Lestón, Jonatan Perez‐Arce, Zoraida Freixa, Ander Centeno‐Pedrazo, Max García‐Melchor, Eduardo J. Garcia‐Suarez   +7 more
wiley   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway

Frontiers in Pharmacology
IntroductionTriple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer to treat. While previous studies have demonstrated that ginsenoside Rh2 induces apoptosis in TNBC cells, the specific molecular targets and underlying ...
Rumeng Ding, Quancheng Kan, Ting Wang, Ran Xiao, Yanan Song, Duolu Li   +5 more
doaj   +1 more source

Ginsenoside Rh2 Reduces Ischemic Brain Injury in Rats

Biological and Pharmaceutical Bulletin, 2004
Ginseng was incubated under mildly acidic conditions and its inhibitory effect on a rat ischemia-reperfusion model was investigated. When ginseng was treated with 0.1% hydrochloric acid at 60 degrees C, its protopanaxadiol saponins were transformed to diasteromeric ginsenoside Rg3 and Delta20-ginsenoside Rg3.
Park, Eun-Kyung, Choo, Min-Kyung, Oh, Jin Kyung, Ryu, Jong Hoon, Kim, Dong-Hyun   +4 more
openaire   +3 more sources

Ginsenoside Rb1 is transformed into Rd and Rh2 by Microbacterium trichothecenolyticum

Journal of Microbiology and Biotechnology, 2013
Ginsenosides are the most important ingredient of ginseng and are known to possess many pharmacological and biological effects. Rb1, a major protopanaxadiol ginsenoside, is the most abundant ginsenoside in Panax ginseng C.A Meyer and can be hydrolyzed into more pharmaceutically potent minor ginsenosides.
Hansoo, Kim, Jeong-Hoon, Kim, Phil Young, Lee, Kwang-Hee, Bae, Sayeon, Cho, Byoung Chul, Park, Heungsop, Shin, Sung Goo, Park   +7 more
openaire   +2 more sources

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, Volume 13, Issue 34, 19 June 2026.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Selective Rh(II)‐Catalyzed Intermolecular Oxyamidation and Acid‐Promoted Nucleophilic Cyclization Cascade of Enamides

ChemistryEurope, Volume 4, Issue 6, June 2026.
A structurally diverse series of 1‐amino‐izidine scaffolds was accessed through a cascade process combining rhodium‐catalyzed nitrene‐transfer oxyamidation with subsequent nucleophilic cyclization under acidic conditions, proceeding via an in situ generated iminium intermediate.
Grégory Jestin, Romain Rey‐Rodriguez, Romane Manguin, Pascal Retailleau, Philippe Dauban, Isabelle Gillaizeau   +5 more
wiley   +1 more source

COMPARATIVE STUDY OF ECHINOCHROME A, OXYGENATED CAROTENOIDS, GINSENOSIDE Rh2, LUTEOLIN DISULFATE AND METFORMIN AS A MEAN TO POTENTIATE ANTITUMOR EFFECT OF DOXORUBICIN

Медицинская иммунология, 2018
This work concerned a comparative study of potentiating effects produced by some drugs of natural origin, as well as metformin, upon antitumor activity of doxorubicin. An increased therapeutic efficacy of doxorubicin used in combination with echinochrome
A. V. Tsybulsky, A. M. Popov, A. A. Klimovich, A. A. Artyukov, E. Ya. Kostetsky, M. D. Veselova   +5 more
doaj   +1 more source

Retention of the Full Visual Opsin Repertoire in Some Australian Cryptozoic Lizards

Ecology and Evolution, Volume 16, Issue 6, June 2026.
This study investigates the link between visual evolution and fossorial habits in the endemic Australian skink genus Lerista. We provide evidence for positive site‐specific selection in all 4 cone opsins, as well as relaxed selection specific to LWS. We also provide evidence of selection linked to limb reduction, an indicator of fossorial adaptation ...
Matthew J. R. Ford, Alastair J. Ludington, Tessa Bradford, Kate L. Sanders, Mark N. Hutchinson, Bruno F. Simões   +5 more
wiley   +1 more source