Results 51 to 60 of about 68,233 (207)

Inhibition of prostatic cancer growth by ginsenoside Rh2

Tumor Biology, 2014
Ginsenoside Rh2 (GRh2) has been reported to have therapeutic effects on some types of cancer, but its effect on prostatic cancer has not been extensively evaluated. Here, we show that GRh2 can substantially inhibit the growth of prostatic cancer in vivo and in vitro.
Qingchuan, Zhang, Bin, Hong, Songhua, Wu, Tianli, Niu   +3 more
openaire   +2 more sources

Ginsenoside Rh2 Suppresses Neovascularization in Xenograft Psoriasis Model [PDF]

Cellular Physiology and Biochemistry, 2015
Background/Aims: Psoriasis is a common inflammatory skin disease of undetermined etiology and poor prognosis. The current therapies have focused on direct inhibition of local inflammation, e.g. through hormone treatments. However, neovascularization plays a critical role in the development of psoriasis but so far no therapies have been developed to ...
Jing Zhou, Yunlu Gao, Xuemei Yi, Yangfeng Ding   +3 more
openaire   +3 more sources

Photoswitching Conduction in Framework Materials

Advanced Functional Materials, EarlyView.
This mini‐review summarizes recent advances in state‐of‐the‐art proton and electron conduction in framework materials that can be remotely and reversibly switched on and off by light. It discusses the various photoswitching conduction mechanisms and the strategies employed to enhance photoswitched conductivity.
Helmy Pacheco Hernandez, Stefan Hecht, Wolfgang Wenzel, Lars Heinke, Mariana Kozlowska   +4 more
wiley   +1 more source

Ginsenoside Rh2 Inhibits NLRP3 Inflammasome Activation and Improves Exosomes to Alleviate Hypoxia-Induced Myocardial Injury

Frontiers in Immunology, 2022
The inflammatory microenvironment after acute myocardial infarction (MI) is a key limiting factor in the clinical application of stem cell transplantation and paracrine exosome therapy.
Zhongwen Qi, Zhongwen Qi, Zhongwen Qi, Zhipeng Yan, Zhipeng Yan, Zhipeng Yan, Yueyao Wang, Yueyao Wang, Yueyao Wang, Nan Ji, Xiaoya Yang, Ao Zhang, Meng Li, Fengqin Xu, Junping Zhang, Junping Zhang   +15 more
doaj   +1 more source

Enhanced production of HD and D_2 molecules on small dust grains in diffuse clouds

, 2003
Motivated by recent observations of deuterated molecules in the interstellar medium, we examine the production of HD and D$_2$ molecules on dust grain surfaces. A mechanism for the enhanced production of these deuterated molecules is studied.
Aronowitz, Azi Lipshtat, Biham, Biham, Brackmann, Brown, Brown, Caselli, Caselli, Caselli, Cazaux, Ceccarelli, Charnley, Charnley, d'Hendecourt, Dalgarno, Draine, Draine, Draine, Duley, Eric Herbst, Gould, Green, Hasegawa, Hasegawa, Hasegawa, Hollenbach, Hollenbach, Hollenbach, Hoogers, Katz, Koehler, Landau, Li, Manicò, Mathis, Mathis, Mathis, Millar, Montroll, Ofer Biham, Pickles, Pirronello, Pirronello, Pirronello, Pirronello, Roberts, Roberts, Roberts, Roberts, Rodgers, Sandford, Schutte, Shalabiea, Shalabiea, Smoluchowski, Smoluchowski, Stantcheva, Stantcheva, Stantcheva, Takahashi, Tielens, van der Tak, Watson, Weingartner, Willacy, Williams   +66 more
core   +1 more source

Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis. [PDF]

, 2015
BackgroundKey effector(s) of mutated KRAS in lung cancer progression and metastasis are unknown. Here we investigated the role of PAK1/Crk axis in transduction of the oncogenic KRAS signal in non-small cell lung cancer (NSCLC).MethodsWe used NSCLC ...
Aljilani, Amir, Lewis, Michael, Lu, Jie, Mortazavi, Fariborz, Pezeshkpour, Gholamhossein, Phan, Ryan, Tamanoi, Fuyuhiko, Trinidad, Kenny   +7 more
core   +2 more sources

3D Printed Multimaterial Microfluidic Transistors

Advanced Materials Technologies, EarlyView.
We introduce a biocompatible, high resolution photopolymer resin that closely mimics the Young's Modulus (elasticity) and reversible stretchability (no hysteresis) of poly(dimethylsiloxane) (PDMS), enabling the fabrication of microfluidic transistors (i.e., microvalves capable of proportional amplification) by multimaterial stereolithography (mSLA ...
Alireza Ahmadianyazdi, Wei Huang, Kaustav A. Gopinathan, Ivan Stepanov, Lisa Horowitz, Ting‐Yuan Tu, Mehmet Toner, Albert Folch   +7 more
wiley   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Magnetic anisotropy and geometrical frustration in the Ising spin-chain system Sr5Rh4O12 [PDF]

, 2006
A structural and thermodynamic study of the newly synthesized single crystal Sr5Rh4O12 is reported. Sr5Rh4O12 consists of a triangular lattice of spin chains running along the c-axis. It is antiferromagnetically ordered below 23 K with the intrachain and
Aasland, Cao, Cao, Collins, G. Cao, Hardy, Hardy, Kageyama, Kudasov, Niitaka, Niitaka, P. Schlottmann, Ramirez, Rayaprol, S. Parkin, Schiffer, Sugiyama, Sugiyama, Wu   +18 more
core   +1 more source

A stereo-selective growth inhibition profile of ginsenoside Rh2 on human colon cancer cells

CyTA - Journal of Food, 2019
We compared the stereo-selective growth inhibition effects of purified enantiomeric pairs of ginsenoside Rh2 (20(S)-ginsenoside Rh2 and 20(R)-ginsenoside Rh2) on human colon cancer cells in vitro with non-invasive real-time cellular analysis. When 50 μM,
Yunju Jeong, Seockmo Ku, Hyun Ju You, Geun Eog Ji   +3 more
doaj   +1 more source