Results 101 to 110 of about 65,503 (295)

A nonhuman primate model of inherited retinal disease. [PDF]

, 2019
Inherited retinal degenerations are a common cause of untreatable blindness worldwide, with retinitis pigmentosa and cone dystrophy affecting approximately 1 in 3500 and 1 in 10,000 individuals, respectively.
Artemyev, Nikolai O, Boyd, Kimberly, Cameron, Ashley, Chen, Rui, Davis, Sarah, Garzel, Laura, Gopalakrishna, Kota N, Harris, R Alan, Huang, Yijun, Kim, Soohyun, Li, Yumei, Liang, Qingnan, Moshiri, Ala, Murphy, Christopher J, Pomerantz, Ori, Raveendran, Muthuswamy, Roberts, Jeffrey, Rogers, Jeffrey, Stout, J Timothy, Thomasy, Sara M, Wang, Jun, Yiu, Glenn   +21 more
core  

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions

Archaeometry, EarlyView.
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith, Manish Arora, Maya Bharatiya, Nicole Leonard, Jian‐xin Zhao, Christine Austin   +5 more
wiley   +1 more source

Albinism in a juvenile rhesus macaque Macaca mulatta (Zimmermann 1780) from the Brahmaputra Valley of Assam, India (Primates: Cercopithecidae)

Natural History Sciences
Color aberrations are rare phenomena in wild mammals and are often associated with genetic disruptions affecting melanin production or deposition. The rhesus macaque Macaca mulatta, one of the most widespread primate species in India, has only rarely ...
Neeraj Bora, Sanghamitra Buragohain, Deep Jyoti Borah, Chiranjib Bora, Sandip Choudhury, Jyotismita Das   +5 more
doaj   +1 more source

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]

, 2017
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa, Pinkerton, Kent, Royer, Christopher, Schelegle, Edward   +3 more
core   +1 more source

The Status and Emerging Developments in Laboratory Animal Science in Asia since 9th AFLAS Congress (2023) until 10th AFLAS Congress (2025)

Animal Models and Experimental Medicine, EarlyView.
Asian Federation of Laboratory Animal Science Associations (AFLAS)
wiley   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Variation in trabecular bone microarchitecture across rhesus macaque (Macaca mulatta) load‐bearing joints

Journal of Anatomy, EarlyView.
Aging of bone density (BV/TV) is regional: Forelimb [left] elements gain bone sporadically (orange) but hind limb elements [right] lose bone globally (blue). Abstract Globally, human population structure is quickly trending older, increasing the prevalence and systemic burden of age‐related skeletal disorders such as osteoporosis.
Cassandra M. Turcotte, Aditi Raghunath, Timothy M. Ryan, Lily J. D. DeMars, Erin Siracusa, Sam K. Patterson, Cayo Biobank Research Unit, Michael L. Platt, Lauren J. N. Brent, Noah Snyder‐Mackler, Samuel E. Bauman, Michael J. Montague, Melween I. Martinez, Scott A. Williams, Susan C. Antón, James P. Higham, Sharon Kuo   +16 more
wiley   +1 more source

Does ulnar curvature covary with locomotion and substrate use in cercopithecids?

Journal of Anatomy, EarlyView.
This study investigates ulnar curvature in cercopithecids in relation to locomotor behaviors, introducing an analysis of anteroposterior and mediolateral curvature, using geometric morphometric on 167 specimens (23 species). Although the two curvatures distinguish arboreal and terrestrial quadrupeds, their moderate covariation suggests that they ...
Nicolas Pappalardo, Laurent Pallas, Julian Karoui‐Canedo, Franck Guy, Guillaume Daver   +4 more
wiley   +1 more source

Effective and stable gene transduction in rhesus macaque iPSCs capable of T-lineage differentiation utilizing the piggyBac system

Regenerative Therapy
Introduction: Genetically modified human induced pluripotent stem cell (iPSC)-based regenerative medicine has substantial potential in the treatment of refractory human diseases.
Masahiro Tanaka, Yoshihiro Iwamoto, Bo Wang, Eri Imai, Munehiro Yoshida, Shoichi Iriguchi, Shin Kaneko   +6 more
doaj   +1 more source