Results 101 to 110 of about 29,826 (216)

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae, Jessica Marie Hunter Alberhasky, Marion Baillet, Debra A. Bangasser, Michael E. Belloy, Anne S. Berry, Chiara Berteotti, Hannah Bow, Rachel Buckley, Jessica Z. K. Caldwell, Matteo Carpi, Benjamin J. Clark, Claire J. Ciampa, Alexander C. Conley, Martin J. Dahl, Zoe R. Donaldson, Alexander J. Ehrenberg, Gillian Einstein, Neus Falgàs, Haley A. Fenlon, Megan C. Fitzhugh, Robert C. Froemke, Clara Gallay, Lea Tenenholz Grinberg, Derek A. Hamilton, Zia Hasan, Oihane Uriarte Huarte, Shaista Jabeen, Heidi I. L. Jacobs, Louis John Kolling, Elouise A. Koops, Sabrina Lenzoni, Claudio Liguori, Riccardo Manca, Catherine A. Marcinkiewcz, Tamunotonye Omoluabi, Rademene Oria, Caitlin A. Orsini, Nancy Elizabeth Ortega, Judy Pa, Nathan S. Pentkowski, Joana B. Pereira, Rhudovic Ramos, Derya Sargin, Abhijit Satpati, Maria Clara Selles, Mabel Seto, Shabana M. Shaik, Shireen Sindi, Gowoon Son, Valentine Ucheagwu, Maxime Van Egroo, Qi Yuan, Michael A. Kelberman   +53 more
wiley   +1 more source

Bottom‐Up Ice Growth Geometry Attenuates Shear Stress and Improves the Cryopreservation of Hematopoietic Stem/Progenitor Cells Under Low DMSO Concentrations

Biotechnology and Bioengineering, Volume 123, Issue 3, Page 582-597, March 2026.
ABSTRACT Studies on cell cryopreservation have been limited by the complexity of the freezing process and challenges on controlling ice formation, managing cooling rates, and optimizing cryoprotectant concentrations. The objective of this study is to evaluate the impact of bottom‐up and conventional radial freezing on the viability of mammalian cells ...
Rafaela Ouro Neves, Pedro Sena Rego, Marta H. G. Costa, Isabel Bogalho, Andreia Duarte, Claúdia L. da Silva, Frederico Castelo Ferreira, Vitor Geraldes, Miguel A. Rodrigues   +8 more
wiley   +1 more source

The ocular surface microbiome of rhesus macaques

Animal Microbiome
Background The ocular surface microbiota (OSM) is important for eye health, and variations in OSM composition have been associated with multiple diseases in humans. Studies of OSM-disease dynamics in humans are confounded by lifestyle factors.
Joelle K. Hass, Arthur G. Fernandes, Michael J. Montague, Armando Burgos-Rodriguez, Melween I. Martinez, Lauren J. N. Brent, Noah Snyder-Mackler, John Danias, Gadi Wollstein, James P. Higham, Amanda D. Melin   +10 more
doaj   +1 more source

Connectivity of the Superior Temporal Polysensory Area With the Presubiculum, Parasubiculum, Entorhinal Cortex, and Claustrum–Endopiriform Complex in the Common Marmoset (Callithrix jacchus)

Journal of Comparative Neurology, Volume 534, Issue 3, March 2026.
The marmoset superior temporal polysensory area was found to have strong reciprocal connectivity with the distal presubiculum, parasubiculum, and proximal (medial) entorhinal cortex and with the claustrum–endopiriform complex, in addition to the rostral–caudal intrinsic connections. Our findings suggest that interconnected circuits exist in these areas,
Yoshiko Honda, Keiko Moriya‐Ito, Nanako Hashimoto, Yasushi Kobayashi   +3 more
wiley   +1 more source

Genomic properties of a Bartonella quintana strain from Japanese macaque (Macaca fuscata) revealed by genome comparison with human and rhesus macaque strains

Scientific Reports
Bartonella quintana, the causative agent of trench fever, is an intracellular bacterium that infects human erythrocytes and vascular endothelial cells. For many years, humans were considered the only natural hosts for B.
Shingo Sato, Emu Nishioka, Hidenori Kabeya, Soichi Maruyama   +3 more
doaj   +1 more source

An Ad26‐MVA‐BN‐based therapeutic vaccine targeting HPV16 and HPV18 related disease is immunogenic in preclinical models and in women with persistent HPV infections

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Immunisation with adenovirus (Ad) vectors followed by Modified Vaccinia Virus Ankara—strain Bavarian Nordic (MVA‐BN) vectors expressing HPV16 and HPV18 engineered antigens induced antigen‐specific polyfunctional T cells in mice, rhesus macaques and persistent HPV16/HPV18 infected human females vaccines (n = 5). These data showed the promise of the Ad26‐
Selina Khan, Satish Boedhoe, Miranda Baert, Jan Serroyen, Thierry Verbinnen, Ariane Volkmann, Markus Kalla, Katrin Weidner, Mathieu Le Gars, Jerry Sadoff, Michal Sarnecki, Jort Vellinga, Jerome Custers, Gert Scheper, Hanneke Schuitemaker, Roland Zahn   +15 more
wiley   +1 more source

Adaptive Genetic Variation in Black‐and‐White Snub‐Nosed Monkeys (Rhinopithecus bieti): Low Diversity and the Role of Balancing Selection

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We investigated the adaptive genetic diversity within a population of Rhinopithecus bieti using amplicon sequencing. From 47 individuals, we identified 16 MHC class I sequences, revealing a low level of adaptive genetic variation. Although evidence for balancing selection, including positive selection and trans‐species polymorphism, was observed, these
Fei Long, Mei‐Jing Ying, Tian‐Qi Shi, Paul A. Garber, Ru‐Liang Pan, Jian‐Dong Lai, Zhi‐Pang Huang, Bao‐Guo Li, Pei Zhang   +8 more
wiley   +1 more source

The Effect of Social Rank on Reproductive Traits Depends on Rank Metric: Evidence From a Group‐Living Carnivore

Ecology and Evolution, Volume 16, Issue 3, March 2026.
In animal societies, one's social rank determines access to resources like food, mates, and allies. Using longitudinal data on 481 spotted hyenas, we tested two common social rank metrics with different mechanistic assumptions to see whether resource access or social constraints could best explain different aspects of reproductive success.
Ella W. White, Oliver P. Höner, Marta Mosna, Viktoriia Radchuk, Sarah Benhaiem, Eve Davidian   +5 more
wiley   +1 more source

Niche Partitioning Promotes Coexistence: Habitat Suitability and Spatial Overlap of Three Sympatric Ungulates in a Subtropical Mountain Reserve

Ecology and Evolution, Volume 16, Issue 3, March 2026.
This study assessed the habitat suitability and spatial niche differentiation of three sympatric ungulates—Black muntjac, Reeves's muntjac, and Wild boar—in the Tongbo Mountain National Nature Reserve, China. Using MaxEnt modeling and niche overlap analysis, we found distinct habitat preferences and hierarchical niche segregation that facilitate ...
Jie Yao, Xueqin Hu, Jun Tian, Feiyan Lv, Ruijie Yang, Zhiqiang Huang, Jiancheng Zhai   +6 more
wiley   +1 more source

Microbial Contributions to Primate Reproduction

Evolutionary Anthropology: Issues, News, and Reviews, Volume 35, Issue 1, March 2026.
ABSTRACT Reproduction is a complex process, and microbes play a far greater role than previously imagined. This review explores the ways that microbiomes influence the rich tapestry of reproductive processes and outcomes within the primate lineage, including pre‐copulatory and post‐copulatory mechanisms.
Silvia Carboni, Abigail E. Asangba, Amanda D. Melin   +2 more
wiley   +1 more source