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Immune-mediated inflammatory disorders include a clinically diverse group of conditions sharing similar pathogenic mechanisms. Conditions such as rheumatoid arthritis, psoriasis, spondyloarthropathy, inflammatory bowel disease and connective tissue diseases are characterised by immune dysregulation and chronic inflammation.
Ally, Mahmood Moosa Tar Mahomed+1 more
openaire +6 more sources
Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally. It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage destruction and bone erosion.
Yen-Ju Lin, Martina Anzaghe, S. Schülke
semanticscholar +1 more source
Molecular and Cellular Heterogeneity in Rheumatoid Arthritis: Mechanisms and Clinical Implications
Rheumatoid arthritis is an autoimmune disease that exhibits significant clinical heterogeneity. There are various treatments for rheumatoid arthritis, including disease-modifying anti-rheumatic drugs (DMARDs), glucocorticoids, non-steroidal anti ...
Jianan Zhao+3 more
semanticscholar +1 more source
Influence of Preoperative Physical Function on Gait 1 Month After Total Knee Arthroplasty
Background : This study aimed to identify the preoperative physical performance factors that predict gait speed and endurance 1 month after total knee arthroplasty (TKA).
So Young Lee+5 more
doaj +1 more source
We investigated the importance of the baseline expression of genes involved in energy generation, as prognostic biomarkers of the treatment response to tofacitinib in patients with rheumatoid arthritis (RA). Peripheral blood samples were obtained from 28
Elena V. Tchetina+4 more
doaj +1 more source
OBJECTIVE The development and validation of Modified Disease Activity Scores (DAS) that include different 28-joint counts. METHODS These scores were developed by canonical discriminant analyses and validated for criterion, correlational, and construct ...
M. Prevoo+5 more
semanticscholar +1 more source
Persistencia de medicamentos biológicos durante ocho años en pacientes con artritis reumatoide y espondiloartritis [PDF]
Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
Balsa, Alejandro+5 more
core +3 more sources
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Young Hoon Kim+5 more
doaj +1 more source
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
A Bucht+65 more
core +2 more sources
Atherosclerosis in Rheumatoid Arthritis [PDF]
There is a growing body of evidence supporting an increased risk of cardiovascular (CV) mortality in patients with rheumatoid arthritis (RA). This is the result of complex mechanisms leading to accelerated atherosclerosis [1]. In this regard, besides classic CV risk factors [2], chronic inflammation [3] and a genetic component [3, 4] have been proposed
Gonzalez-Gay, Miguel A+3 more
openaire +3 more sources