Results 131 to 140 of about 44,129 (257)

The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment

British Journal of Pharmacology, EarlyView.
Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton, Fraser Nunn, Erika Lace, Álvaro Lorente‐Macías, Rachel Toth, Asier Unciti‐Broceta, Tim G. Hales   +6 more
wiley   +1 more source

Australian and New Zealand Glaucoma Society (ANZGS) Consensus on Interventional Glaucoma

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Traditional reactive ‘wait and see’ approaches in glaucoma management often result in unacceptable rates of permanent vision loss. This consensus defines a proactive ‘interventional glaucoma’ framework tailored for the Australian and New Zealand healthcare context. Methods A modified Delphi consensus process was utilised, consisting
Graham A. Lee, Lance Liu, Ridia Lim, Rajiv Shah, Robert J. Casson, Keith R. Martin, Helen Danesh‐Meyer, Ashish Agar, Jennifer C. Fan Gaskin, Judy Y. Ku, Geoffrey Chan, Anna Galanopoulos, Shamira Perera   +12 more
wiley   +1 more source

Cold plasma treatment for oral lichen planus: a retrospective case collection and proposal of a new clinical score

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer, Hans‐Robert Metelmann, Mohamed Falougy, Wolfram Kaduk, Lasse Kremer, Georg Daeschlein   +5 more
wiley   +1 more source

Rho-associated kinase 1 (ROCK1); ROCK2 [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Trust in skincare and topical therapies in atopic dermatitis or psoriasis: a German cross‐sectional study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trust in therapy impacts adherence and satisfaction in chronic inflammatory skin diseases, including atopic dermatitis (AD) and psoriasis (PSO). This study assessed and compared trust in skincare and topical therapies and explored influencing factors among AD and PSO patients.
Svenja Royeck, Anna Daphne Bamidis, Conrad Weckbecker, Silke C. Hofmann, Sonja Ständer, Stefan W Schneider, Angelika Weigel, Natalija Novak, Dagmar Wilsmann‐Theis, Galina Balakirski   +9 more
wiley   +1 more source

Rho/Rho-associated kinase pathway in glaucoma

International Journal of Oncology, 2013
JING WANG, XIAOHONG LIU, YISHENG ZHONG
openaire   +2 more sources

Out‐of‐pocket costs and time spent on disease management by vitiligo patients: a cross‐sectional questionnaire study in German‐speaking countries

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives The financial and time‐related burden of patients with vitiligo remains insufficiently studied. This study aimed to quantify out‐of‐pocket costs (OOPC) and time expenditure for vitiligo management and the associated sociodemographic, clinical, and behavioral factors in German‐speaking countries.
Christine Gasteiger, Michael Hindelang, Stefanie Ziehfreund, Hannah Wecker, Tilo Biedermann, Alexander Zink   +5 more
wiley   +1 more source

Deep brain stimulation outcomes and management of childhood‐onset dystonia and associated hyperkinetic movements disorders

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To examine longitudinal changes in self‐selected goals and dystonia severity over 1 year, 2 years, and 5 years after deep brain stimulation (DBS) in children and young people (CYP) with dystonia and other hyperkinetic movement disorders, using CYP and caregiver reports.
Sinead Barkey, Laura Ainaga, Eva Maria Navarrete Muñoz, Verity McClelland, Keyoumars Ashkan, Richard Selway, Harutomo Hasegawa, Daniel E Lumsden, Jean‐Pierre Lin, Hortensia Gimeno   +9 more
wiley   +1 more source

Implications of Rho GTPase signaling in cancer immunotherapy. [PDF]

Biochem Soc Trans
Cai M, Guo F, Zheng Y.
europepmc   +1 more source

The insulin‐like growth factor system and the progression of renal complications of type 2 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Chronic kidney disease is associated with dysregulation of the insulin‐like growth factor (IGF) system. Alterations in IGF bioavailability, driven by IGF binding proteins (IGFBPs), may influence the decline in renal function. However, the longitudinal relationship between baseline IGF‐I, IGF‐II, IGFBPs and progression of kidney ...
Adrian Heald, Yasitha lllangasekera, Andreas Matheou, Ram Prakash Narayanan, Stephen White, Hellena Habte‐Asres, Abigail Lay, Liliana Shalamanova, William Ollier, Graham A. Hitman, Ritwika Mallik, Philip A. Kalra, Martin Whyte, J. Martin Gibson   +13 more
wiley   +1 more source