Results 151 to 160 of about 44,129 (257)

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco, David Uroz‐Torres, Ana Soriano‐Lerma, Miguel Soriano, Jose Antonio García‐Salcedo, Maria Teresa Arias‐Moliz   +5 more
wiley   +1 more source

Early On‐Treatment Change in SALT as a Pragmatic Predictor of Ritlecitinib Response in Moderate‐To‐Severe Alopecia Areata: A Real‐World Cohort Study

International Journal of Dermatology, EarlyView.
Ritlecitinib induced rapid clinical improvement in moderate‐to‐severe alopecia areata in real‐world practice. Early change in SALT at Week 12 strongly discriminated Week‐24 responders, supporting a pragmatic treat‐to‐target checkpoint, alongside improvements in clinician‐reported and patient‐reported outcomes and a favorable safety profile.
Giuseppe Gallo, Isotta Giunipero di Corteranzo, Pietro Quaglino, Simone Ribero, Francois Rosset   +4 more
wiley   +1 more source

Green Tea Polyphenol (-)-Epigallocatechin-3-gallate Protects Endothelial Barrier Function via Myosin Phosphatase and Rho-Kinase. [PDF]

Int J Mol Sci
Wakasugi R, Shiraki A, Mitsui R, Nishida S, Nishizaki A, Shibata S, Fukuda R, Suzuki K, Kaneko-Kawano T.   +8 more
europepmc   +1 more source

Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective

Immunology, EarlyView.
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac, Carolina do Prado Servian, Fernanda de Oliveira Feitosa de Castro, João Lucas Lima Calandrini de Azevedo, Ronaldo Moraes Preto, Miriam Leandro Dorta, Daniela Espíndola Antunes, Simone Gonçalves Fonseca   +7 more
wiley   +1 more source

Decoding Rho GTPase signalling networks in directed cell migration. [PDF]

Front Cell Dev Biol
Mishra YG, Indumathi A, Khumukcham SS, Manavathi B.   +3 more
europepmc   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities. [PDF]

Biochem Soc Trans
Beaudin A, Lefrançois P, Laurin M.
europepmc   +1 more source

Rho-Associated Kinase Inhibitors: Potential Future Treatments for Glaucoma.

Journal of ophthalmic & vision research, 2014
Ramin Daneshvar, Nima Amini
openaire   +3 more sources

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Phosphoproteomics unveils the signaling dynamics in neuronal cells stimulated with insulin and insulin-like growth factors. [PDF]

Cell Commun Signal
Ushakumary MG, Sontag RL, Posso C, Fillmore TL, Topping ME, Olson HM, De Jager PL, Bennett DA, Arvanitakis Z, Petyuk VA.   +9 more
europepmc   +1 more source