Results 91 to 100 of about 82,160 (288)
Measuring irreversibility from learned representations of biological patterns [PDF]
arXiv, 2023 Thermodynamic irreversibility is a crucial property of living matter. Irreversible processes maintain spatiotemporally complex structures and functions characteristic of living systems. In high-dimensional biological dynamics, robust and general quantification of irreversibility remains a challenging task due to experimental noise and nonlinear ...
arxiv
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. [PDF]
The EMBO Journal, 1996 The small GTP binding protein Rho is implicated in cytoskeletal responses to extracellular signals such as lysophosphatidic acid to form stress fibers and focal contacts. Here we have purified a Rho-interacting protein with a molecular mass of approximately 164 kDa (p164) from bovine brain. This protein bound to GTPgammaS (a non-hydrolyzable GTP analog)
Mikako Ito +9 more
openaire +3 more sources
iMeta, EarlyView.Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang +17 more
wiley +1 more source
Rac and Rho GTPases in cancer cell motility control
Cell Communication and Signaling, 2010 Rho GTPases represent a family of small GTP-binding proteins involved in cell cytoskeleton organization, migration, transcription, and proliferation.
Parri Matteo, Chiarugi Paola
doaj +1 more source
Phase diagram of a semiflexible polymer chain in a $θ$ solvent: application to protein folding [PDF]
, 1995 We consider a lattice model of a semiflexible homopolymer chain in a bad solvent. Beside the temperature $T$, this model is described by (i) a curvature energy $\varepsilon_h$, representing the stiffness of the chain (ii) a nearest-neighbour attractive energy $\varepsilon_v$, representing the solvent (iii) the monomer density $\rho={N \over \Omega ...
arxiv +1 more source
rho-rho-N and rho-rho-Delta molecules with $J^P=5/2^{+}$ and $J^P=7/2^{+}$ [PDF]
Euro.Phys. J. A (2011) 47:127, 2011 The rho-rho-N and rho-rho-Delta three-body systems have been studied within the framework of the fixed center approximation of Faddeev equation. The rho-rho interaction in isospin I=0, spin S=2 is strongly attractive, and so are the N-rho, Delta-rho interactions. This leads to bound states of both rho-rho-N and rho-rho-Delta.
arxiv +1 more source
Evidence for the involvement of the Rho GTP‐binding protein in egg activation of the ascidian Halocynthia roretzi [PDF]
Development, Growth & Differentiation, 1995 Eggs of the ascidian Halocynthia roretzi are activated by insemination and by treatment with calcium ionophore, leading to elevation of the vitelline coat. Here we describe the effects on egg activation of microinjection of guanosine 5′‐(γ thio) triphosphate (GTPγS, a non‐hydrolyzable GTP analog), heparin (an antagonist of the inositol 1,4,5 ...
Hideyoshi Yokosawa, Satoshi Toratani
openaire +3 more sources
Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation
PROTEOMICS, EarlyView.ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic +2 more
wiley +1 more source
Frontiers in Oncology, 2020 Although we currently have a good understanding of the role C-X-C chemokine receptor type 4 (CXCR4) plays in T cell acute lymphoblastic leukemia (T-ALL), the mechanism of CXCR4-mediated T-ALL migration remains elusive.
Jixian Luo +3 more
doaj +1 more source
Aging Cell, EarlyView.We show that genetic and pharmacological inhibition of the metabotropic glutamate receptor, DmGluRA extends Drosophila lifespan, improves stress tolerance and alters early‐life locomotion. Several markers indicative of reduced ribosomal biogenesis, a hallmark of longevity, were also detected in these flies.
Cui Guan +4 more
wiley +1 more source