Results 81 to 90 of about 2,823,744 (183)
Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy +2 more
wiley +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
Food Frontiers, Volume 7, Issue 5, September 2026.The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter +20 more
wiley +1 more source
Complex interplay between RAS GTPases and RASSF effectors regulates subcellular localization of YAP
EMBO ReportsRAS GTPases bind effectors to convert upstream cues to changes in cellular function. Effectors of classical H/K/NRAS are defined by RBD/RA domains which recognize the GTP-bound conformation of these GTPases, yet the specificity of RBD/RAs for over 160 ...
Swati Singh +4 more
doaj +1 more source
Regulation of Cdc42 for polarized growth in budding yeast
Microbial Cell, 2020 The Rho GTPase Cdc42 is a central regulator of cell polarity in diverse cell types. The activity of Cdc42 is dynamically controlled in time and space to enable distinct polarization events, which generally occur along a single axis in response to spatial
Kristi E. Miller +2 more
doaj +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
Liver International, Volume 46, Issue 9, September 2026.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
The Arabidopsis ppi1 mutant is specifically defective in the expression, chloroplast import, and accumulation of photosynthetic proteins [PDF]
, 2003 The import of nucleus-encoded proteins into chloroplasts is mediated by translocon complexes in the envelope membranes. A component of the translocon in the outer envelope membrane, Toc34, is encoded in Arabidopsis by two homologous genes, atTOC33 and ...
Baldwin, Amy +27 more
core +1 more source
Molecular Plant Pathology, Volume 27, Issue 9, September 2026.Upon activation by an unknown signal, DrdR targets FleQ, inhibiting its ATPase activity and DNA binding ability. This blocks FleQ from activating the transcription of flagellar genes, downregulating gene expression and suppressing swimming motility. ABSTRACT Response regulators (RRs) of two‐component signalling systems (TCSs) containing tandem receiver
Pei‐Dong Ren +6 more
wiley +1 more source
K-Ras mediated murine epidermal tumorigenesis Is dependent upon and associated with elevated Rac1 activity [PDF]
, 2011 A common goal for potential cancer therapies is the identification of differences in protein expression or activity that would allow for the selective targeting of tumor vs. normal cells. The Ras proto-oncogene family (K-Ras, H-Ras and N-Ras) are amongst
Samuel, M. +14 more
core +2 more sources
Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice
Frontiers in Molecular Neuroscience, 2018 ARHGEF6 belongs to the family of guanine nucleotide exchange factors (GEFs) for Rho GTPases, and it specifically activates Rho GTPases CDC42 and RAC1.
Chengwen Zhu +35 more
doaj +1 more source