Interaction of recombinant rho A GTP‐binding proteins with photoexcited rhodopsin [PDF]
FEBS Letters, 1990 The small molecular mass GTP‐binding proteins rho A, B and C are targets for ADP‐ribosyltransferase activity of the botulinum exoenzyme C3. The possible interaction of recombinant rho A proteins expressed in E. coli with photoexcited rhodopsin was studied by reconstitution with bovine rod outer segment (ROS) membranes depleted of endogenous GTP‐binding
Wieland, Thomas +5 more
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Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins. [PDF]
PLoS ONE, 2017 The Rnd family of proteins, Rnd1, Rnd2 and Rnd3, are atypical Rho family GTPases, which bind to but do not hydrolyse GTP. They interact with plexins, which are receptors for semaphorins, and are hypothesised to regulate plexin signalling.
Thomas Wylie +3 more
doaj +1 more source
Frontiers in Chemistry, 2021 Rac1 is a small signaling protein, which belongs to the Rho subfamily of Ras superfamily. It is activated by binding GTP and inactivated by exchanging GDP for GTP.
Chunwen Zheng +10 more
doaj +1 more source
Fluoride Activation of the Rho Family GTP-binding Protein Cdc42Hs [PDF]
Journal of Biological Chemistry, 1998 Aluminum tetrafluoride (AlF4-) activation of heterotrimeric G-protein alpha-subunits is a well established aspect of the biochemistry of these proteins; however, until recently it has been thought that AlF4- does not mediate effects on the Ras superfamily of low molecular weight GTP-binding proteins.
G R, Hoffman +3 more
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Novel split-luciferase-based genetically encoded biosensors for noninvasive visualization of Rho GTPases. [PDF]
PLoS ONE, 2013 Rho family GTPases are critical regulators of many important cellular processes and the dysregulation of their activities is implicated in a variety of human diseases including oncogenesis and propagation of malignancy.
Weibing Leng +10 more
doaj +1 more source
Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus [PDF]
, 1999 Synaptic NMDA-type glutamate receptors are anchored to the second of three PDZ (PSD-95/Discs large/ZO-1) domains in the postsynaptic density (PSD) protein PSD-95.
Apperson, Michelle +3 more
core +1 more source
RHGF-2 is an essential Rho-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1 in Caenorhabditis elegans. [PDF]
PLoS ONE, 2012 RhoGEF proteins activate the Rho family of small GTPases and thus play a key role in regulating fundamental cellular processes such as cell morphology and polarity, cell cycle progression and gene transcription.
Li Lin +5 more
doaj +1 more source
Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]
, 1999 CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Oliferenko, S. +8 more
core +1 more source
Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]
, 2013 Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick +5 more
core +4 more sources
PAKing up to the endothelium [PDF]
, 2009 Angiogenesis recapitulates the growth of blood vessels that progressively expand and remodel into a highly organized and stereotyped vascular network. During adulthood, endothelial cells that formed the vascular wall retain their plasticity and can be ...
Armelle Le Guelte +3 more
core +6 more sources