Results 21 to 30 of about 2,823,744 (183)

Computer vision profiling of neurite outgrowth mordphodynamics reveals spatio-temporal modularity of Rho GTPase signaling [PDF]

, 2014
Neurite outgrowth is essential to build the neuronal processes that produce axons and dendrites that connect the adult brain. In cultured cells, the neurite outgrowth process is highly dynamic, and consists of a series of repetitive morphogenetic sub ...
Fusco, Ludovico
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RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific [PDF]

, 2004
Hypoxia induces vasoconstriction of pulmonary arteries through contraction of smooth muscle cells (SMCs). The GTPase RhoA regulates smooth muscle contractility and actin cytoskeletal remodeling through the Rho-associated kinase ( ROCK).
Bailly, K, Ridley, A J, Haworth, SG, Ridley, AJ, Hall, SM, Hall, S M, Haworth, S G   +6 more
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BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility [PDF]

, 2006
Background The reciprocal (9;22) translocation fuses the bcr (breakpoint cluster region) gene on chromosome 22 to the abl (Abelson-leukemia-virus) gene on chromosome 9.
Martin Ruthardt, Beissert Tim, Ruthardt, Martin, Ruthardt Martin, Puccetti, Elena, Zheng Xiaomin, Elena Puccetti, Tim Beissert, Zheng, Xiaomin, Xiaomin Zheng, Beissert, Tim, Güller, Saskia, Güller Saskia, Saskia Güller, Puccetti Elena   +14 more
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Rho GTPases and regulation of cell migration and polarization in human corneal epithelial cells. [PDF]

PLoS ONE, 2013
PURPOSE:Epithelial cell migration is required for regeneration of tissues and can be defective in a number of ocular surface diseases. This study aimed to determine the expression pattern of Rho family small G-proteins in human corneal epithelial cells ...
Aihua Hou, Li Xian Toh, Kah Hui Gan, Khee Jin Ryan Lee, Edward Manser, Louis Tong   +5 more
doaj   +1 more source

Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes [PDF]

, 2006
Peer ...
Pokhilko, Alexandra V, Goryachev, Andrew B, Alexandra V Pokhilko, Goryachev Andrew B, Andrew B Goryachev, Pokhilko Alexandra V   +5 more
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Comparative Proteomic Analysis of Anti-Cancer Mechanism by Periplocin Treatment in Lung Cancer Cells

Cellular Physiology and Biochemistry, 2014
Background: Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones and tendons, palpitations or shortness of breath and lower extremity edema in traditional medicine. Our previous findings suggested that periplocin could inhibit
Zejun Lu, Qi Song, Jinliang Yang, Xiangfei Zhao, Xinhong Zhang, Ping Yang, Jingbo Kang   +6 more
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The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering [PDF]

, 2004
Glycine receptors (GlyRs) and specific subtypes of GABA(A) receptors are clustered at synapses by the multidomain protein gephyrin, which in turn is translocated to the cell membrane by the GDP-GTP exchange factor collybistin.
Ward, H, Harvey, R.J., Alldred, Melissa J., Smart, T.G., Luscher, B, Duguid, Ian C, Lingenfelter, S E, Duguid, IC, Ward, H., Lingenfelter, Sue E., Alldred, M.J., Harvey, Robert J., Pearce, B R, Lundgren, J.D., Harvey, K, Owen, Michael John, Pearce, Brian R., Beatty, S.E., Smart, Trevor G., Owens, Max J., Keep, N H, Harvey, RJ, Lingenfelter, S.E., Harvey, Robert J, Keep, NH, Lundgren, J, Owen, MJ, Lund University., Ward, Hamish, Smart, T G, Pearce, B.R., Lüscher, Bernhard, Beatty, Sarah E., Lingenfelter, SE, Lundgren, Johan,, Keep, Nicholas H., Lundgren, Johan, Luscher, B., Harvey, K., Smart, TG, Alldred, M J, Beatty, SE, Owen, M J, Beatty, S E, Alldred, MJ, Rees, MI, Harvey, Kirsten, Duguid, I C, Rees, Mark I., Rees, M I, Duguid, I.C., Pearce, BR, Mark Rees, Rees, M.I.   +53 more
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Flux Analysis in Process Models via Causality [PDF]

Electronic Proceedings in Theoretical Computer Science, 2010
We present an approach for flux analysis in process algebra models of biological systems. We perceive flux as the flow of resources in stochastic simulations. We resort to an established correspondence between event structures, a broadly recognised model
Ozan Kahramanoğulları
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The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase [PDF]

, 2002
Toc34 is a protein of the chloroplast outer envelope membrane that acts as receptor for preproteins containing a transit sequence. The recognition of preproteins by Toc34 is regulated by GTP binding and phosphorylation.
Soll, J., Jelic, M., Schleiff, E., Motzkus, M., Sveshnikova, N., Hörth, P.   +5 more
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Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Renoprotective Effect of Rho-Kinase Inhibitor in Hypertensive Glomerulosclerosis

Journal of Pharmacological Sciences, 2006
.: Among the GTP-binding proteins, Rho is known to function as a molecular switch in various cellular functions. Among the Rho effectors, the cellular function and signal transduction of Rho-kinase have been extensively studied.
Toshio Nishikimi, Hiroaki Matsuoka
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