Results 61 to 70 of about 82,160 (288)

Cdc42/Rac Interactive Binding Containing Effector Proteins in Unicellular Protozoans With Reference to Human Host: Locks of the Rho Signaling

open access: yesFrontiers in Genetics, 2022
Small GTPases are the key to actin cytoskeleton signaling, which opens the lock of effector proteins to forward the signal downstream in several cellular pathways. Actin cytoskeleton assembly is associated with cell polarity, adhesion, movement and other
Preeti Umarao   +2 more
doaj   +1 more source

Glass Transition in a 2D Lattice Model [PDF]

open access: yesJour. Phys. A 33, 1729 (2000), 1999
The dynamics of compaction of hard cross-shaped pentamers on the 2D square lattice is investigated. The addition of new particles is controlled by diffusive relaxation. It is shown that the filling process terminates at a glassy phase with a limiting coverage density \rho_{rcp}=0.171626(3), lower than the density of closest packing \rho_{cp}=0.2, and ...
arxiv   +1 more source

Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus [PDF]

open access: yes, 1999
Synaptic NMDA-type glutamate receptors are anchored to the second of three PDZ (PSD-95/Discs large/ZO-1) domains in the postsynaptic density (PSD) protein PSD-95.
Apperson, Michelle   +3 more
core   +1 more source

RhoA and Rac1 in Liver Cancer Cells: Induction of Overexpression Using Mechanical Stimulation

open access: yesMicromachines, 2020
Liver cancer, especially hepatocellular carcinoma (HCC), is an aggressive disease with an extremely high mortality rate. Unfortunately, no promising markers are currently available for the early diagnosis of this disease.
Sharda Yadav   +2 more
doaj   +1 more source

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

open access: yes, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick   +5 more
core   +4 more sources

Roles of Rap1 signaling in tumor cell migration and invasion

open access: yesCancer Biology & Medicine, 2017
Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization.
Yi-Lei Zhang   +4 more
doaj   +1 more source

Cell Division Control Protein 42 Interacts With Hepatitis E Virus Capsid Protein and Participates in Hepatitis E Virus Infection

open access: yesFrontiers in Microbiology, 2021
Hepatitis E Virus (HEV) causes viral hepatitis in humans worldwide, while a subset of HEV species, avian HEV, causes hepatitis-splenomegaly syndrome in chickens.
Mengnan Fan   +10 more
doaj   +1 more source

On the possibility of extending the Nore-Frenkel generalized law of correspondent states to non-isotropic patchy interactions [PDF]

open access: yesJ. Phys. Chem. B; (Letter); 2007; 111(33); 9702-9705., 2007
Colloidal systems (and protein solutions) are often characterized by attractive interactions whose range is much smaller than the particle size. When this is the case and the interaction is spherical, systems obey a generalized law of correspondent states (GLCS), first proposed by Noro and Frenkel [ J.Chem.Phys. 113, 2941 (2000) ].
arxiv   +1 more source

Unique and differential protein signatures within the mononuclear cells of HIV-1 and HCV mono-infected and co-infected patients

open access: yesClinical Proteomics, 2012
Background Pathogenesis of liver damage in patients with HIV and HCV co-infection is complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is increasing little is known about the pathophysiology that mediates the rapid ...
Boukli Nawal M   +9 more
doaj   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai   +8 more
wiley   +1 more source

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