Results 51 to 60 of about 61,508 (249)

Transition to Quorum Sensing in an Agrobacterium Population: A Stochastic Model. [PDF]

, 2005
Understanding of the intracellular molecular machinery that is responsible for the complex collective behavior of multicellular populations is an exigent problem of modern biology.
Zhang, Lian-Hui, Travis Lee (274971), Keng Boon Wee (43442), Lee Travis, Da-Jun Toh (274970), Andrew B Goryachev, Wee Keng Boon, Lian-Hui Zhang, Lian-Hui Zhang (119133), Keng Boon Wee, Zhang, Hai-Bao, Toh, Da-Jun, Wee, Keng Boon, Goryachev, Andrew B, Hai-Bao Zhang, Andrew B Goryachev (274969), Da-Jun Toh, Lee, Travis, Goryachev Andrew B, Toh Da-Jun, Hai-Bao Zhang (274972), Zhang Hai-Bao, Travis Lee, Zhang Lian-Hui   +23 more
core   +1 more source

The role of statins in lung cancer

Archives of Medical Science, 2021
Lung cancer is one of the most common causes of cancer-related mortality in the 21st century. Statins as inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase not only reduce the cholesterol levels in the blood and decrease the risk of ...
Fatemeh Amin, Farzaneh Fathi, Željko Reiner, Maciej Banach, Amirhossein Sahebkar   +4 more
doaj   +1 more source

The Role of Mg2+ Cofactor in the Guanine Nucleotide Exchange and GTP Hydrolysis Reactions of Rho Family GTP-binding Proteins*

Journal of Biological Chemistry, 2000
The biological activities of Rho family GTPases are controlled by their guanine nucleotide binding states in cells. Here we have investigated the role of Mg2+ cofactor in the guanine nucleotide binding and hydrolysis processes of the Rho family members ...
Baolin Zhang, Yaqin Zhang, Zhi-Xin Wang, Yi Zheng   +3 more
semanticscholar   +1 more source

Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes. [PDF]

The Journal of cell biology, 1995
To study an endocytotic role of the GTP-binding protein RhoA in Xenopus oocytes, we have monitored changes in the surface expression of sodium pumps, the surface area of the oocyte and the uptake of the fluid-phase marker inulin. Xenopus oocytes possess intracellular sodium pumps that are continuously exchanged for surface sodium pumps by constitutive ...
Schmalzing, G., Richter, H., Hansen, A., Schwarz, W., Just, I., Aktories, K.   +5 more
openaire   +3 more sources

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Ripoll, Camille, Ovádi, Judit, Norris, Vic, Amar, Patrick, Thellier, Michel, Legent, Guillaume   +5 more
core   +1 more source

Cdc42/Rac Interactive Binding Containing Effector Proteins in Unicellular Protozoans With Reference to Human Host: Locks of the Rho Signaling

Frontiers in Genetics, 2022
Small GTPases are the key to actin cytoskeleton signaling, which opens the lock of effector proteins to forward the signal downstream in several cellular pathways. Actin cytoskeleton assembly is associated with cell polarity, adhesion, movement and other
Preeti Umarao, Pragyan Parimita Rath, Samudrala Gourinath   +2 more
doaj   +1 more source

Bimodal expression of RHOH during myelomonocytic differentiation: Implications for the expansion of AML differentiation therapy

eJHaem, 2021
RhoH is an unusual member of the Rho family of small GTP‐binding proteins in that it lacks GTPase activity. Since the RhoH protein is constantly bound by GTP, it is constitutively active and controlled predominantly by changes in quantitative expression.
Sylvie Galiègue‐Zouitina, Qiangwei Fu, Céline Carton‐Latreche, Nicolas Poret, Meyling Cheok, Frédéric Leprêtre, Martin Figeac, Bruno Quesnel, Hassiba El Bouazzati, Carl S Shelley   +9 more
doaj   +1 more source

Vav family exchange factors: Potential regulator in atherosclerosis

Biochemistry and Biophysics Reports
The Vav family of guanosine nucleotide exchange factors (GEFs) regulates the phosphorylation of tyrosinase, influencing various physiological and pathological processes by modulating the binding of Rho GTPases to GDP/GTP.
Yu Zhang, Yongwei Ren, Tao Zhou, Zhengtao Qian, Zhengyang Bao   +4 more
doaj   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source